Duke University Medical Center neurobiologists have discovered how neurons in the brain "reset" when they are overly active. This molecular reset switch works to increase or decrease the sensitivity of brain cells to stimulation by their neighbors. Such "homeostatic plasticity" is critical for the brain to adapt to changes in the environment -- either to avoid having its neurons swamped by increased activity of a neural pathway, or rendered too insensitive to detect triggering impulses from other neurons when neural activity is low. This plasticity is distinct from the more rapid changes in neural circuits laid down early during the formation of memories, said the scientists.
Michael D. Ehlers, M.D., Ph.D., Assistant Professor, department of neurobiology, Duke University Medical Center
PHOTO CREDIT: This photo is the property of Duke University.
According to the researchers, their basic studies provide long-sought clues to how neurons protect themselves during stroke, epilepsy, and spinal cord injury. Also, their findings may help explain diverse brain changes that occur during early childhood and that go awry in later stages of life in Alzheimers or Parkinsons disease.
The researchers, led by Assistant Professor of Neurobiology Michael Ehlers, M.D., published their findings in the Oct. 30, 2003, issue of the journal Neuron. Other authors are Yuanyue Mu, Ph.D., Takeshi Otsuka, Ph.D., April Horton and Derek Scott. The research was supported by the National Institutes of Health, the American Heart Association and a Broad Scholars Award.
Dennis Meredith | dukemed news
Small but versatile; key players in the marine nitrogen cycle can utilize cyanate and urea
10.12.2018 | Max-Planck-Institut für Marine Mikrobiologie
Carnegie Mellon researchers probe hydrogen bonds using new technique
10.12.2018 | Carnegie Mellon University
What if a sensor sensing a thing could be part of the thing itself? Rice University engineers believe they have a two-dimensional solution to do just that.
Rice engineers led by materials scientists Pulickel Ajayan and Jun Lou have developed a method to make atom-flat sensors that seamlessly integrate with devices...
Scientists at the University of Stuttgart and the Karlsruhe Institute of Technology (KIT) succeed in important further development on the way to quantum Computers.
Quantum computers one day should be able to solve certain computing problems much faster than a classical computer. One of the most promising approaches is...
New Project SNAPSTER: Novel luminescent materials by encapsulating phosphorescent metal clusters with organic liquid crystals
Nowadays energy conversion in lighting and optoelectronic devices requires the use of rare earth oxides.
Scientists have discovered the first synthetic material that becomes thicker - at the molecular level - as it is stretched.
Researchers led by Dr Devesh Mistry from the University of Leeds discovered a new non-porous material that has unique and inherent "auxetic" stretching...
Scientists from the Theory Department of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science (CFEL) in Hamburg have shown through theoretical calculations and computer simulations that the force between electrons and lattice distortions in an atomically thin two-dimensional superconductor can be controlled with virtual photons. This could aid the development of new superconductors for energy-saving devices and many other technical applications.
The vacuum is not empty. It may sound like magic to laypeople but it has occupied physicists since the birth of quantum mechanics.
10.12.2018 | Event News
06.12.2018 | Event News
03.12.2018 | Event News
10.12.2018 | Life Sciences
10.12.2018 | Physics and Astronomy
10.12.2018 | Life Sciences