Northwestern University researchers have found that caspases, a family of protein-cutting enzymes involved in programmed cell death (apoptosis), may be a missing link in the chain of molecular events leading to Alzheimer´s disease.
Alzheimer´s disease is a neurodegenerative condition affecting an estimated 4 million Americans that causes memory loss and, ultimately, dementia. Patients with this disease have abnormal deposits (plaques) of protein fragments called amyloid-beta surrounding neurons in their brain and "tangles" of a protein called tau inside brain cells.
For years, scientists have been debating which of these two events – plaques or tangles – is the primary cause of Alzheimer´s disease. Recent studies have suggested that amyloid promotes the assembly of tau into tangles, but, until now, the actual mechanism by which this occurs was poorly understood.
Elizabeth Crown | EurekAlert!
3D technology lets us look into the distant past
20.05.2019 | Eberhard Karls Universität Tübingen
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20.05.2019 | California Institute of Technology
Engineers at the University of Tokyo continually pioneer new ways to improve battery technology. Professor Atsuo Yamada and his team recently developed a...
With a quantum coprocessor in the cloud, physicists from Innsbruck, Austria, open the door to the simulation of previously unsolvable problems in chemistry, materials research or high-energy physics. The research groups led by Rainer Blatt and Peter Zoller report in the journal Nature how they simulated particle physics phenomena on 20 quantum bits and how the quantum simulator self-verified the result for the first time.
Many scientists are currently working on investigating how quantum advantage can be exploited on hardware already available today. Three years ago, physicists...
'Quantum technologies' utilise the unique phenomena of quantum superposition and entanglement to encode and process information, with potentially profound benefits to a wide range of information technologies from communications to sensing and computing.
However a major challenge in developing these technologies is that the quantum phenomena are very fragile, and only a handful of physical systems have been...
Working group led by physicist Professor Ulrich Nowak at the University of Konstanz, in collaboration with a team of physicists from Johannes Gutenberg University Mainz, demonstrates how skyrmions can be used for the computer concepts of the future
When it comes to performing a calculation destined to arrive at an exact result, humans are hopelessly inferior to the computer. In other areas, humans are...
Scientists develop a molecular recording tool that enables in vivo lineage tracing of embryonic cells
The beginning of new life starts with a fascinating process: A single cell gives rise to progenitor cells that eventually differentiate into the three germ...
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