Howard Hughes Medical Institute researchers are moving closer to understanding how the global pattern of the skeleton of mammals is formed during development. In an exceptionally demanding series of experiments, the researchers knocked out entire sets of two families of genes suspected in playing a central role in establishing the pattern of the skeleton in the mammalian embryo.
Their findings regarding the "paralogous" gene families known as Hox10 and Hox11 establish that the genes play important roles in orchestrating the construction of the ribs, spine and limb bones. Paralogous genes are sets of genes that have overlapping function. They arose during evolution through gene duplication.
The studies on Hox10 and Hox11 were published in the July 18, 2003, issue of the journal Science by HHMI investigator Mario R. Capecchi and colleague Deneen M. Wellik, who are both at the University of Utah.
Jim Keeley | EurekAlert!
New findings help to better calculate the oceans’ contribution to climate regulation
14.11.2018 | Jacobs University Bremen gGmbH
How algae and carbon fibers could sustainably reduce the athmospheric carbon dioxide concentration
14.11.2018 | Technische Universität München
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
Physicists at ETH Zurich demonstrate how errors that occur during the manipulation of quantum system can be monitored and corrected on the fly
The field of quantum computation has seen tremendous progress in recent years. Bit by bit, quantum devices start to challenge conventional computers, at least...
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14.11.2018 | Life Sciences