Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Researchers detect receptor for day/night cycles

24.06.2003


It’s been something of a mystery to scientists - how are blind mice able to synchronize their biological rhythms to day and night? New research by a team of scientists, including one from the University of Toronto, seems to have uncovered the answer.

Rods and cones in the outer retina are the eyes’ main photoreceptors, explains Nicholas Mrosovsky, professor emeritus in zoology at U of T. When these rods and cones degenerate, mammals and animals become blind. Despite this, however, some animals can synchronize their biological clocks to the day/night cycle, a problem that has perplexed scientists for the past decade.

"We believed there must be some other specialized receptor for detecting night and day. We now have evidence that this long sought-after photoreceptor is a layer of cells, located in the inner retina, that contain melanopsin, a pigment chemically related to other opsins [a type of protein] found in the rods and cones of the outer retina."



In their study, the researchers deleted melanopsin from the inner retinal cells of transgenic mice. Mrosovsky found that melanopsin-free mice could not synchronize their biological rhythms to day/night cycles or react normally to light stimuli. This research may be applicable to humans who are blind but who have the melanopsin receptor. They may still be able to synchronize their biological rhythms, he says.


Recently published online in Nature, this research was supported by the U.S. National Eye Institute, the U.K. Biotechnology and Biological Sciences Research Council, the Wellcome Trust and the Canadian Institutes of Health Research.

Additional Contact: Professor Emeritus Nicholas Mrosovsky, Department of Zoology, 416-978-8506, mro@zoo.utoronto.ca

Janet Wong | EurekAlert!
Further information:
http://www.utoronto.ca/

More articles from Life Sciences:

nachricht Microscope measures muscle weakness
16.11.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg

nachricht Good preparation is half the digestion
16.11.2018 | Max-Planck-Institut für Stoffwechselforschung

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: UNH scientists help provide first-ever views of elusive energy explosion

Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.

Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...

Im Focus: A Chip with Blood Vessels

Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.

Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...

Im Focus: A Leap Into Quantum Technology

Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.

In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...

Im Focus: Research icebreaker Polarstern begins the Antarctic season

What does it look like below the ice shelf of the calved massive iceberg A68?

On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.

Im Focus: Penn engineers develop ultrathin, ultralight 'nanocardboard'

When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure

Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

“3rd Conference on Laser Polishing – LaP 2018” Attracts International Experts and Users

09.11.2018 | Event News

On the brain’s ability to find the right direction

06.11.2018 | Event News

European Space Talks: Weltraumschrott – eine Gefahr für die Gesellschaft?

23.10.2018 | Event News

 
Latest News

Purdue cancer identity technology makes it easier to find a tumor's 'address'

16.11.2018 | Health and Medicine

Good preparation is half the digestion

16.11.2018 | Life Sciences

Microscope measures muscle weakness

16.11.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>