Animal Models Offer Newborn Opportunity to Permanently Rescue Insulin-making Cells and Possibly Even Protect Against Future Onset
A common condition that leads to low birthweight babies may predispose the infants to obesity and diabetes later in life by denying cells in the pancreas access to the chemical signals they need to mature, according to researchers at the University of Pennsylvania School of Medicine. Moreover, the condition, which they have successfully modeled in rodents, may be reversed soon after birth by the administration of hormones that stimulate the maturation of the pancreatic beta cells, which produce insulin. Their findings suggest a way of preventing diabetes in people at-risk for the disease by boosting the creation of beta cells soon after birth.
According to Rebecca A. Simmons, MD, assistant professor in Penns Department of Pediatrics, "the condition, called intrauterine growth retardation (IUGR), is generally caused by the inability of a developing fetus to receive adequate nutrition and can effect as many as one in 10 newborns." Diminished fetal growth is due to a number of different processes such as high blood pressure and intrauterine infections. Epidemiological studies have also shown that there is a strong link between IUGR and the development of obesity and diabetes in adulthood. The Penn researchers believe the link may be due to the decreased formation of blood vessels in the pancreas.
Greg Lester | EurekAlert!
Barium ruthenate: A high-yield, easy-to-handle perovskite catalyst for the oxidation of sulfides
16.07.2018 | Tokyo Institute of Technology
The secret sulfate code that lets the bad Tau in
16.07.2018 | American Society for Biochemistry and Molecular Biology
For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.
To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...
For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.
Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...
Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.
A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...
Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.
"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....
Ultra-short, high-intensity X-ray flashes open the door to the foundations of chemical reactions. Free-electron lasers generate these kinds of pulses, but there is a catch: the pulses vary in duration and energy. An international research team has now presented a solution: Using a ring of 16 detectors and a circularly polarized laser beam, they can determine both factors with attosecond accuracy.
Free-electron lasers (FELs) generate extremely short and intense X-ray flashes. Researchers can use these flashes to resolve structures with diameters on the...
13.07.2018 | Event News
12.07.2018 | Event News
03.07.2018 | Event News
16.07.2018 | Physics and Astronomy
16.07.2018 | Life Sciences
16.07.2018 | Earth Sciences