Researchers looking inside a pathogenic soil bacterium have found an organelle, a subcellular pouch, existing independently from the plasma membrane. The discovery within a prokaryotic organism challenges the theory on the origin of eukaryotic organelles and suggests a targeted approach to killing many disease-causing organisms.
Acidocalcisomes (the black spheres) as viewed in a trypanosome, a family of parasites that cause African sleeping sickness, Chagas disease and leishmaniasis and the first organisms where Docampo found this organelle. The cell is approximately 10 microns long and 4 microns wide. Courtesy of Kildare Miranda
"The organelle we found in the bacterium Agrobacterium tumefaciens is practically identical to the organelle called acidocalcisome in unicellular eukaryotes," said Roberto Docampo, a professor of veterinary pathobiology in the College of Veterinary Medicine at the University of Illinois at Urbana-Champaign.
Docampo began researching these organelles in 1994. He soon determined that a tiny granule in yeast, fungi and bacteria, thought to be for storage, was a fully operational organelle containing pyrophosphatase, a pump-like enzyme that allows proton transport. He named it an acidocalcisome for its acidic and calcium components. In 2000, he reported its existence in Plasmodium berghei, a malaria-causing eukaryotic parasite.
Jim Barlow | UIUC
Brought to light – chromobodies reveal changes in endogenous protein concentration in living cells
21.09.2018 | NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen
A one-way street for salt
21.09.2018 | Julius-Maximilians-Universität Würzburg
The building blocks of matter in our universe were formed in the first 10 microseconds of its existence, according to the currently accepted scientific picture. After the Big Bang about 13.7 billion years ago, matter consisted mainly of quarks and gluons, two types of elementary particles whose interactions are governed by quantum chromodynamics (QCD), the theory of strong interaction. In the early universe, these particles moved (nearly) freely in a quark-gluon plasma.
This is a joint press release of University Muenster and Heidelberg as well as the GSI Helmholtzzentrum für Schwerionenforschung in Darmstadt.
Then, in a phase transition, they combined and formed hadrons, among them the building blocks of atomic nuclei, protons and neutrons. In the current issue of...
Thin-film solar cells made of crystalline silicon are inexpensive and achieve efficiencies of a good 14 percent. However, they could do even better if their shiny surfaces reflected less light. A team led by Prof. Christiane Becker from the Helmholtz-Zentrum Berlin (HZB) has now patented a sophisticated new solution to this problem.
"It is not enough simply to bring more light into the cell," says Christiane Becker. Such surface structures can even ultimately reduce the efficiency by...
A study in the journal Bulletin of Marine Science describes a new, blood-red species of octocoral found in Panama. The species in the genus Thesea was discovered in the threatened low-light reef environment on Hannibal Bank, 60 kilometers off mainland Pacific Panama, by researchers at the Smithsonian Tropical Research Institute in Panama (STRI) and the Centro de Investigación en Ciencias del Mar y Limnología (CIMAR) at the University of Costa Rica.
Scientists established the new species, Thesea dalioi, by comparing its physical traits, such as branch thickness and the bright red colony color, with the...
Scientists have succeeded in observing the first long-distance transfer of information in a magnetic group of materials known as antiferromagnets.
An international team of researchers has mapped Nemo's genome, providing the research community with an invaluable resource to decode the response of fish to...
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