Arf gene became more effective in stemming cell growth when it joined forces with p53
Researchers at St. Jude Childrens Research Hospital have looked back in evolutionary time and identified what may be a gene that was once only moderately effective in slowing down cellular reproduction, until it linked up with a more efficient set of genes to create a powerful anti-cancer response.
The gene, called Arf, was already known to have cancer-suppressing activity. Arf responds to cancer-causing environments by activating the well-known tumor suppressor gene, p53. In turn, p53 activates a battery of other genes to stop cell growth or, in extreme cases, to trigger cell death in response to a variety of harmful conditions, such as DNA damage or activation of oncogenes (cancer-causing genes). In fact, loss of Arf or p53 is a common event in many human cancers.
Bonnie Cameron | EurekAlert!
New findings help to better calculate the oceans’ contribution to climate regulation
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14.11.2018 | Technische Universität München
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
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Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
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On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
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Physicists at ETH Zurich demonstrate how errors that occur during the manipulation of quantum system can be monitored and corrected on the fly
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