Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Advances in the Separation of Nucleosides

11.02.2003


Researchers in Oxford University’s Department of Inorganic Chemistry have devised a method for the selective separation and recovery of nucleoside phosphates from complex reaction mixtures using Layered Double Hydroxide (LDH) materials.



Nucleoside phosphates are used extensively in industry as intermediates or additives in nutraceutical and pharmaceutical preparation, as well as in medical and separation science. In particular many new antiviral agents are based on nucleosides. Supplying the potential demand for nucleoside phosphates poses a challenge to current technological approaches. Therefore, simple purification processes for the recovery of large quantities of valuable nucleoside phosphates contained within mixtures of other nucleoside phosphates is needed.

In the new Oxford method, LDH materials are used as fast, efficient and high capacity ion exchange materials for the removal of organic and inorganic anions from aqueous streams because they have the capacity to form intercalation compounds with the desired anions. The majority of LDHs are made from anionic clays or clay mineral materials. Following the intercalation step, the desired nucleoside phosphate compounds are removed from within the LDH material by simple chemical means to leave the LDH material intact and ready for re-use. The main competitive advantages of this method lie within the high purity of the resultant nucleoside phosphates, the ease of scale up and the fewer number of process steps. Additionally, the LDH material is designed for use with conventional filtration technologies.


Isis Innovation, Oxford University’s technology transfer company, has filed a UK priority patent application for this technology and welcomes contact from potential commercial partners.

Jennifer Johnson | alfa
Further information:
http://www.isis-innovation.com/licensing/867.html

More articles from Life Sciences:

nachricht Nonstop Tranport of Cargo in Nanomachines
20.11.2018 | Max-Planck-Institut für molekulare Zellbiologie und Genetik

nachricht Researchers find social cultures in chimpanzees
20.11.2018 | Universität Leipzig

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Nonstop Tranport of Cargo in Nanomachines

Max Planck researchers revel the nano-structure of molecular trains and the reason for smooth transport in cellular antennas.

Moving around, sensing the extracellular environment, and signaling to other cells are important for a cell to function properly. Responsible for those tasks...

Im Focus: UNH scientists help provide first-ever views of elusive energy explosion

Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.

Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...

Im Focus: A Chip with Blood Vessels

Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.

Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...

Im Focus: A Leap Into Quantum Technology

Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.

In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...

Im Focus: Research icebreaker Polarstern begins the Antarctic season

What does it look like below the ice shelf of the calved massive iceberg A68?

On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Optical Coherence Tomography: German-Japanese Research Alliance hosted Medical Imaging Conference

19.11.2018 | Event News

“3rd Conference on Laser Polishing – LaP 2018” Attracts International Experts and Users

09.11.2018 | Event News

On the brain’s ability to find the right direction

06.11.2018 | Event News

 
Latest News

Nonstop Tranport of Cargo in Nanomachines

20.11.2018 | Life Sciences

Researchers find social cultures in chimpanzees

20.11.2018 | Life Sciences

When AI and optoelectronics meet: Researchers take control of light properties

20.11.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>