Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

’Sticky’ DNA crystals promise new way to process information

07.02.2003


Imagine information stored on something only a hundredth the size of the next generation computer chip--and made from nature’s own storage molecule, DNA. A team led by Richard Kiehl, a professor of electrical engineering at the University of Minnesota, has used the selective "stickiness" of DNA to construct a scaffolding for closely spaced nanoparticles that could exchange information on a scale of only 10 angstroms (an angstrom is one 10-billionth of a meter). The technique allows the assembly of components on a much smaller scale and with much greater precision than is possible with current manufacturing methods, Kiehl said. The work is published in a recent issue of the Journal of Nanoparticle Research.



"In a standard silicon-based chip, information processing is limited by the distance between units that store and share information," said Kiehl. "With these DNA crystals, we can lay out devices closely so that the interconnects are very short. If nanoparticles are spaced even 20 angstroms apart on such a DNA crystal scaffolding, a chip could hold 10 trillion bits per square centimeter--that’s 100 times as much information as in the 64 Gigabit D-RAM memory projected for 2010. By showing how to assemble nanoscale components in periodic arrangements, we’ve taken the first step toward this goal."

Eventually, a chip made from DNA crystals and nanoparticles could be valuable in such applications as real-time image processing, Kiehl said. Nanocomponents could be clustered in pixel-like "cells" that would process information internally and also by "talking" to other cells. The result could be improved noise filtering and detection of edges or motion. Someday, the technology may even help computers identify images with something approaching the speed of the human eye and brain, said Kiehl.


The team devised a DNA scaffolding for arrays of nanoparticles of gold, but the scaffolding could also hold arrays of carbon nanotubes or other molecules. Information could be stored as an electrical charge on certain nanoparticles; the presence or absence of charge would constitute one bit of information. Alternatively, nanoparticles could be magnetic, and the magnetic states would be read as information. Because DNA strands contain four chemical bases spaced every 3.4 angstroms, information might be stored on that small a scale, Kiehl said.

To manufacture the scaffolding, the researchers took advantage of the fact that each base spontaneously pairs up with, or "sticks to," one of the other bases to form the famous DNA double helix. The team synthesized four different two-dimensional "tiles" of DNA, each tile having an extension that sticks to the extension on another tile. Like self-assembling jigsaw pieces, the tiles joined themselves into a flat crystal with a repeating pattern. One tile had a stretch of DNA that extended above the plane of the tile; to this the researchers anchored a spherical, 55-atom nanoparticle of gold. Under an electron microscope, the gold nanoparticles appeared as regular lines of bright spots. A regular pattern of nanoparticles is important in arranging them to process or store information.

"Gold is a metal, and a matrix between metals and organic molecules like DNA is very hard to make," Kiehl said. "If we can make DNA scaffolding for gold, we think we can do it for carbon nanotubes and other organic molecules. The technique is well suited to laying out locally interconnected circuitry, which is of great interest for circumventing the interconnect bottleneck-- the well-known problem where wires, rather than devices (transistors), limit computing speed."

Other scientists have used DNA as nanoparticle "glue," but such arrangements are prone to structural flaws, which limits their usefulness, said Kiehl. In contrast, the virtually perfect arrangement of molecules within a DNA crystal allows precise control over the arrangement of the particles.

Among the next steps for the researchers is to demonstrate that nanoparticles bound to the DNA crystals can function electrically.

"We’re working on instrumentation to do electrical characterization of gold nanoparticles and other nanocomponents on DNA," said Kiehl. "We hope to show, for example, that DNA doesn’t interfere with the electrical functioning of the nanocomponents."

The work was supported by the National Science Foundation.

Deane Morrison | EurekAlert!
Further information:
http://www.umn.edu/

More articles from Life Sciences:

nachricht How algae and carbon fibers could sustainably reduce the athmospheric carbon dioxide concentration
14.11.2018 | Technische Universität München

nachricht NIH scientists illuminate causes of hepatitis b virus-associated acute liver failure
14.11.2018 | NIH/National Institute of Allergy and Infectious Diseases

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A Chip with Blood Vessels

Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.

Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...

Im Focus: A Leap Into Quantum Technology

Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.

In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...

Im Focus: Research icebreaker Polarstern begins the Antarctic season

What does it look like below the ice shelf of the calved massive iceberg A68?

On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.

Im Focus: Penn engineers develop ultrathin, ultralight 'nanocardboard'

When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure

Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...

Im Focus: Coping with errors in the quantum age

Physicists at ETH Zurich demonstrate how errors that occur during the manipulation of quantum system can be monitored and corrected on the fly

The field of quantum computation has seen tremendous progress in recent years. Bit by bit, quantum devices start to challenge conventional computers, at least...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

“3rd Conference on Laser Polishing – LaP 2018” Attracts International Experts and Users

09.11.2018 | Event News

On the brain’s ability to find the right direction

06.11.2018 | Event News

European Space Talks: Weltraumschrott – eine Gefahr für die Gesellschaft?

23.10.2018 | Event News

 
Latest News

How algae and carbon fibers could sustainably reduce the athmospheric carbon dioxide concentration

14.11.2018 | Life Sciences

NIH scientists illuminate causes of hepatitis b virus-associated acute liver failure

14.11.2018 | Life Sciences

The unintended consequences of dams and reservoirs

14.11.2018 | Earth Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>