UCSF-led scientists have identified the first "master" molecule in the cell nucleus that controls the action of hundreds of different genes at once through its action on enzymes. The broad-acting molecule affects enzymes that restructure chromosomes, exposing genes to proteins that can then trigger key gene processes, including the start of protein production and copying and repairing of genes.
The molecules broad effect on a number of genes may allow organisms – including humans -- to respond quickly to stress, the scientists say. The research finding is based on studies of yeast, but the same molecule is present in humans and all higher organisms. Mutations that affect enzymes involved in chromosome restructuring have been linked to human cancers.
The study is published by SCIENCE through its Science Express web site. The paper will appear in a later print issue of SCIENCE.
Wallace Ravven | EurekAlert!
Russian scientists show changes in the erythrocyte nanostructure under stress
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How the intestinal fungus Candida albicans shapes our immune system
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An international research team including astronomers from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has combined radio telescopes from five continents to prove the existence of a narrow stream of material, a so-called jet, emerging from the only gravitational wave event involving two neutron stars observed so far. With its high sensitivity and excellent performance, the 100-m radio telescope in Effelsberg played an important role in the observations.
In August 2017, two neutron stars were observed colliding, producing gravitational waves that were detected by the American LIGO and European Virgo detectors....
Up to now, OLEDs have been used exclusively as a novel lighting technology for use in luminaires and lamps. However, flexible organic technology can offer much more: as an active lighting surface, it can be combined with a wide variety of materials, not just to modify but to revolutionize the functionality and design of countless existing products. To exemplify this, the Fraunhofer FEP together with the company EMDE development of light GmbH will be presenting hybrid flexible OLEDs integrated into textile designs within the EU-funded project PI-SCALE for the first time at LOPEC (March 19-21, 2019 in Munich, Germany) as examples of some of the many possible applications.
The Fraunhofer FEP, a provider of research and development services in the field of organic electronics, has long been involved in the development of...
For the first time, an international team of scientists based in Regensburg, Germany, has recorded the orbitals of single molecules in different charge states in a novel type of microscopy. The research findings are published under the title “Mapping orbital changes upon electron transfer with tunneling microscopy on insulators” in the prestigious journal “Nature”.
The building blocks of matter surrounding us are atoms and molecules. The properties of that matter, however, are often not set by these building blocks...
Scientists at the University of Konstanz identify fierce competition between the human immune system and bacterial pathogens
Cell biologists from the University of Konstanz shed light on a recent evolutionary process in the human immune system and publish their findings in the...
Laser physicists have taken snapshots of carbon molecules C₆₀ showing how they transform in intense infrared light
When carbon molecules C₆₀ are exposed to an intense infrared light, they change their ball-like structure to a more elongated version. This has now been...
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