Genes that are inappropriately turned on play a critical role in triggering some diseases. For researchers, the trick is learning how to deactivate these genes to treat illnesses. In a step toward reaching that goal, scientists at Stanford University Medical Center have developed a gene-therapy technique to switch off genes in mice. The finding could potentially lead to ways of treating such diseases as cancer, hepatitis C and AIDS.
In plants and lower organisms such as flies or worms, researchers can experimentally switch off genes by inserting RNA. Genes normally produce RNA molecules, which the cell uses as a template to create proteins. The injected RNA interferes with the usual order of events and prevents protein from being made - effectively shutting down the gene.
"RNA inhibition has been shown to work in lower organisms, but there was some question about whether it would work in mammals," said Mark Kay, MD, PhD, professor of genetics and pediatrics at Stanford.
Polarization of Br2 molecule in vanadium oxide cluster cavity and new alkane bromination
13.07.2020 | Kanazawa University
Researchers present concept for a new technique to study superheavy elements
13.07.2020 | Johannes Gutenberg-Universität Mainz
Biochemists at Martin Luther University Halle-Wittenberg (MLU) have used a standard electron cryo-microscope to achieve surprisingly good images that are on par with those taken by far more sophisticated equipment. They have succeeded in determining the structure of ferritin almost at the atomic level. Their results were published in the journal "PLOS ONE".
Electron cryo-microscopy has become increasingly important in recent years, especially in shedding light on protein structures. The developers of the new...
New insight into the spin behavior in an exotic state of matter puts us closer to next-generation spintronic devices
Aside from the deep understanding of the natural world that quantum physics theory offers, scientists worldwide are working tirelessly to bring forth a...
Kiel physics team observed extremely fast electronic changes in real time in a special material class
In physics, they are currently the subject of intensive research; in electronics, they could enable completely new functions. So-called topological materials...
Solar cells based on perovskite compounds could soon make electricity generation from sunlight even more efficient and cheaper. The laboratory efficiency of these perovskite solar cells already exceeds that of the well-known silicon solar cells. An international team led by Stefan Weber from the Max Planck Institute for Polymer Research (MPI-P) in Mainz has found microscopic structures in perovskite crystals that can guide the charge transport in the solar cell. Clever alignment of these "electron highways" could make perovskite solar cells even more powerful.
Solar cells convert sunlight into electricity. During this process, the electrons of the material inside the cell absorb the energy of the light....
Empa researchers have succeeded in applying aerogels to microelectronics: Aerogels based on cellulose nanofibers can effectively shield electromagnetic radiation over a wide frequency range – and they are unrivalled in terms of weight.
Electric motors and electronic devices generate electromagnetic fields that sometimes have to be shielded in order not to affect neighboring electronic...
07.07.2020 | Event News
02.07.2020 | Event News
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13.07.2020 | Physics and Astronomy
13.07.2020 | Life Sciences
13.07.2020 | Life Sciences