The US saw nearly 20,000 cases of Lyme disease in 2006 and there are up to 2,000 cases a year in the UK, a figure that is increasing steadily. Now scientists at the Centers for Disease Control and Prevention in Fort Collins, Colorado, USA, have developed an injection that protects against two severe diseases transmitted by tick bites: Lyme disease and Anaplasmosis.
“Along the North-eastern seaboard of the US, ticks are often co-infected with the bacteria that cause Lyme disease and Anaplasmosis,” says Dr Nordin Zeidner. “Currently there is no vaccine to protect against either organism. We have shown that a single injection of sustained-release antibiotics can prevent both diseases in mice.”
A single dose of doxycycline given orally is only 20-30% effective at preventing these diseases in mice. The researchers found that a new formulation of doxycycline hyclate that is programmed to release the drug over a 20 day period is 100% effective.
“The underlying copolymer formulation has been in use for over 20 years. It has no adverse effect on humans and it can be programmed to release a drug over several weeks to several months,” says Dr Zeidner. “We plan to test the doxycycline formulation to develop different release kinetics and delivery methods. For example, a slow release patch could be used in conjunction with current recommended protection against ticks, such as repellents and personal tick checks.”
Lucy Goodchild | alfa
New way to look at cell membranes could change the way we study disease
19.11.2018 | University of Oxford
Controlling organ growth with light
19.11.2018 | European Molecular Biology Laboratory
Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.
Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
19.11.2018 | Event News
09.11.2018 | Event News
06.11.2018 | Event News
19.11.2018 | Materials Sciences
19.11.2018 | Information Technology
19.11.2018 | Life Sciences