In Sweden, a form of hemorrhagic fever with renal syndrome called nephropathia epidemica occurs primarily in the northern parts of the country. It is a zoonosis, that is, an infectious disease that is normally transmitted between animals and humans when a bank vole, for instance, releases Puumala hantavirus via its saliva, urine, and feces.
Normally humans become infected by breathing in dust polluted by virus from bank vole secretions or by direct contact with the animal.
It has recently been shown in South America that the Andes hantavirus, which is closely related to the Puumala hantavirus, can in some cases be transmitted among humans. The Umeå team's findings indicate that a possible path of contagion for hantavirus disease might be human saliva.
During last year's outbreak of nephropathia epidemica in northern Sweden, saliva samples were collected from 14 patients in Västerbotten County, and virus RNA was found in the saliva in ten cases. It is not clear whether the virus found in human saliva is capable of infecting another human, but this question is now being studied intensively.
Nephropathia epidemica, is a serious disease, and patients coming to hospitals often have high fevers, headaches, muscle pain, and abdominal pain, and are in generally poor condition. In Sweden some 2,200 cases of nephropathia epidemica were reported in 2007, and more than 800 of them were from Västerbotten County. Up to 30% of those who were diagnosed with nephropathia epidemica wind up in the hospital, and in Västerbotten County two deaths occurred in 2007. In South and North America infections by close relatives of the Puumala hantavirus lead to death in 40% of cases.
The Umeå team consists of Associate Professor Magnus Evander and resident specialist physician and doctoral candidate Lisa Pettersson at the Division for Virology and Assistant Professor Clas Ahlm and Post-Doctoral Fellow Jonas Klingström at the Division for Infectious Diseases, all at the Department of Clinical Microbiology, Umeå University. Other co-authors are Jonas Hardestam and Åke Lundkvist, Swedish Institute for Infectious Disease Control, Stockholm. The findings will soon be published in the journal Emerging Infectious Diseases.
For more information, please contact Associate Professor Magnus Evander, Department of Clinical Microbiology, Umeå University, phone: +46 (0)90-785 17 90, e-mail: Magnus.Evander@climi.umu.se
Pressofficer Hans Fällman; firstname.lastname@example.org; +46-70 691 28 29
Hans Fällman | idw
Platinum nanoparticles for selective treatment of liver cancer cells
15.02.2019 | ETH Zurich
New molecular blueprint advances our understanding of photosynthesis
15.02.2019 | DOE/Lawrence Berkeley National Laboratory
For the first time, an international team of scientists based in Regensburg, Germany, has recorded the orbitals of single molecules in different charge states in a novel type of microscopy. The research findings are published under the title “Mapping orbital changes upon electron transfer with tunneling microscopy on insulators” in the prestigious journal “Nature”.
The building blocks of matter surrounding us are atoms and molecules. The properties of that matter, however, are often not set by these building blocks...
Scientists at the University of Konstanz identify fierce competition between the human immune system and bacterial pathogens
Cell biologists from the University of Konstanz shed light on a recent evolutionary process in the human immune system and publish their findings in the...
Laser physicists have taken snapshots of carbon molecules C₆₀ showing how they transform in intense infrared light
When carbon molecules C₆₀ are exposed to an intense infrared light, they change their ball-like structure to a more elongated version. This has now been...
The so-called Abelian sandpile model has been studied by scientists for more than 30 years to better understand a physical phenomenon called self-organized...
Physicists from the University of Basel have developed a new method to examine the elasticity and binding properties of DNA molecules on a surface at extremely low temperatures. With a combination of cryo-force spectroscopy and computer simulations, they were able to show that DNA molecules behave like a chain of small coil springs. The researchers reported their findings in Nature Communications.
DNA is not only a popular research topic because it contains the blueprint for life – it can also be used to produce tiny components for technical applications.
11.02.2019 | Event News
30.01.2019 | Event News
16.01.2019 | Event News
15.02.2019 | Physics and Astronomy
15.02.2019 | Physics and Astronomy
15.02.2019 | Life Sciences