Atherosclerosis in the coronary arteries is associated with a risk of future heart disease, and it is therefore important to find risk markers for atherosclerotic disease.
“When the heart beats, the body's blood vessels increase in diameter, and there is also movement alongside the blood vessels, known as longitudinal displacement, or tLod,” explains researcher Sara Svedlund from the Department of Molecular and Clinical Medicine at the Sahlgrenska Academy. “It was not previously possible to tell whether this movement had any impact on health, as there was a lack of adequate measurement techniques.”
In her thesis, Svedlund investigated whether ultrasound technique could be used to study tLoD in the blood vessels in the neck. This would provide a simple and painless method of identifying patients at increased risk of coronary artery disease.
She used an advanced imaging analysis technique to study movement in the carotid artery using standard clinical ultrasound images. The method was tested on around 500 people, both patients with suspected coronary artery disease and healthy volunteers. It has also been transferred to experimental animal models for more in-depth studies in future.
Patients with reduced longitudinal displacement along the carotid artery have more extensive atherosclerosis in that artery, impaired heart function and a greater tendency to suffer from a shortage of oxygen in the heart. In a follow-up study, Svedlund has also been able to show that this new risk marker can predict the risk of future cardiovascular events.
“Today's methods look only at the thickness of the artery walls when identifying atherosclerosis. Our technique shows that longitudinal displacement in the carotid artery reflects both the degree of atherosclerosis in the artery and heart function. This new method may therefore give us additional information and enable us to predict which patients run an increased risk of future heart disease. We will follow up these interesting findings in further studies to establish the technique which potentially can be used in clinical routine in the future.”
Scientists uncover the role of a protein in production & survival of myelin-forming cells
19.07.2018 | Advanced Science Research Center, GC/CUNY
NYSCF researchers develop novel bioengineering technique for personalized bone grafts
18.07.2018 | New York Stem Cell Foundation
For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.
To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...
For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.
Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...
Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.
A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...
Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.
"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....
Ultra-short, high-intensity X-ray flashes open the door to the foundations of chemical reactions. Free-electron lasers generate these kinds of pulses, but there is a catch: the pulses vary in duration and energy. An international research team has now presented a solution: Using a ring of 16 detectors and a circularly polarized laser beam, they can determine both factors with attosecond accuracy.
Free-electron lasers (FELs) generate extremely short and intense X-ray flashes. Researchers can use these flashes to resolve structures with diameters on the...
13.07.2018 | Event News
12.07.2018 | Event News
03.07.2018 | Event News
19.07.2018 | Earth Sciences
19.07.2018 | Power and Electrical Engineering
19.07.2018 | Materials Sciences