This was shown in a study conducted by scientists from the Transfacultary Research Platform at the University of Basel. By measuring the motor excitability, conclusions can be drawn as to the general cortical excitability – as well as to cognitive performance.
Working memory allows the temporary storage of information such as memorizing a phone number for a short period of time. Studies in animals have shown that working memory processes among others depend on the excitability of neurons in the prefrontal cortex.
Moreover, there is evidence that motor neuronal excitability might be related to the neuronal excitability of other cortical regions. Researchers from the Psychiatric University Clinics (UPK Basel) and the Faculty of Psychology in Basel have now studied if the excitability of the motor cortex correlates with working memory performance– results were positive.
«The motor cortical excitability can be easily studied with transcranial magnetic stimulation», says Nathalie Schicktanz, doctoral student and first author of the study. During this procedure, electromagnetic impulses with increasing intensity are applied over the motor cortex. For subjects with high motor excitability already weak impulses are sufficient to trigger certain muscles – such as those of the hand – to show a visible twitch.
Conclusions for other cortical regions
In the present study, that included 188 healthy young subjects, the scientists were able to show that subjects with a high motor excitability had increased working memory performance as compared to subjects with a low excitability. «By measuring the excitability of the motor cortex, conclusions can be drawn as to the excitability of other cortical areas», says Schicktanz.
«The findings help us to understand the importance of neuronal excitability for cognitive processes in humans», adds Dr. Kyrill Schwegler, co-author of the study. The results might also have important clinical implications, as working memory deficits are a component of many neuropsychiatric disorders, such as schizophrenia or attention deficit hyperactivity disorder. In a next step, the scientists plan to study the relation between neuronal excitability and memory on a molecular level.
The study is part of a project lead by Prof. Dominique de Quervain and Prof. Andreas Papassotiropoulos. The project uses transcranial magnetic stimulation to study the cognitive functions in humans. The goal is to identify the neurobiological and molecular mechanisms of human memory.Original citation
Prof. Dominique de Quervain, Faculty of Psychology, Cognitive Neuroscience, phone: +41 61 267 02 37, email : email@example.com
Olivia Poisson | Universität Basel
Microscope measures muscle weakness
16.11.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg
Good preparation is half the digestion
16.11.2018 | Max-Planck-Institut für Stoffwechselforschung
Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.
Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
09.11.2018 | Event News
06.11.2018 | Event News
23.10.2018 | Event News
16.11.2018 | Health and Medicine
16.11.2018 | Life Sciences
16.11.2018 | Life Sciences