The German Research Foundation (DFG) has established a new Collaborative Research Center on "Nanodimensional polymer therapeutics for tumor therapy" (CRC 1066) at Johannes Gutenberg University Mainz (JGU) and the Max Planck Institute for Polymer Research (MPI-P). Starting in October 2013, the Collaborative Research Center will receive grants totaling approximately EUR 11 million over four years to develop a nanoparticle-based cancer therapy to combat melanoma as an immunogenic tumor model.
The Mainz scientists will focus on a form of cancer immunotherapy that is specifically suitable for permanently eliminating minimal residual disease, such as hidden metastases. The new CRC is notable for its interdisciplinary approach: chemists will study the synthetic feasibility and the structure-property relationships of carrier materials, while immunologists and biomedical specialists develop models for the optimal use of such carriers – in the form of a new combination therapy for activating the body’s immune response against the cancer.The coordinator of the new DFG-funded Collaborative Research Center is Professor Rudolf Zentel from the Institute of Organic Chemistry at Johannes Gutenberg University Mainz. Assistant coordinators are Professor Stephan Grabbe from the Department of Dermatology at the Mainz University Medical Center and Professor Katharina Landfester from the Max Planck Institute for Polymer Research in Mainz. In addition, the Board of Directors will include Professor Detlef Schuppan from the Department of Internal Medicine I at the Mainz University Medical Center and Dr. Mathias Barz from the JGU Institute of Organic Chemistry as a representative of young researchers.
Petra Giegerich | idw
Microscope measures muscle weakness
16.11.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg
Good preparation is half the digestion
16.11.2018 | Max-Planck-Institut für Stoffwechselforschung
Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.
Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
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16.11.2018 | Life Sciences
16.11.2018 | Life Sciences