New cyclotron produces radioactive isotopes for nuclear chemistry to be applied in basic research and the development of clinical applications
A new particle accelerator will further enhance the research landscape at Johannes Gutenberg University Mainz (JGU). It is to be employed to conduct research into potential applications of medical relevance. The new cyclotron has been installed in a basement structure of the Institute of Nuclear Chemistry on the Gutenberg Campus.
It will be used to generate short half-life isotopes, which will be principally used for fundamental research but are also required for the medical imaging technique known as positron emission tomography (PET). The cost of this large-scale research device amounts to about EUR 1 million provided by the German Research Foundation (DFG) and the Rhineland-Palatinate Research Initiative. Commissioning of the new cyclotron is planned for spring 2016.
The cyclotron is a ring-shaped particle accelerator that occupies a floor space of some 7.5 square meters and has a height of two meters. It weighs about 50 tons and a crane had to be used to lower it through a hole in the ceiling into the designated basement room. In addition to the cyclotron room, the new structure has a technical and control center together with an access lock. The structure is linked directly to the Institute of Nuclear Chemistry extension building and has all safety-relevant features.
As it will be able to accelerate protons to an energy of 9.7 mega-electron volts (MeV), the cyclotron at Mainz University can be used to generate the two radioactive elements fluorine-18 and carbon-11. These will be mainly employed for chemical and pharmaceutical research purposes but are also necessary for the PET medical diagnostic imaging technique.
F-18 and C-11 have short half-lives of just 110 and 20 minutes respectively. It is thus necessary to generate them near the location at which they are to be used to ensure that they are available in sufficient quantities. It has not previously been possible in Mainz to create radiopharmaceuticals labeled with C-11 because of its particularly short half-life. The new accelerator has now made this feasible.
"The cyclotron will enhance our currently existing infrastructure and eliminate a bottleneck in the production of radioactive nuclides," explained Professor Frank Rösch of the JGU Institute of Nuclear Chemistry. "It will significantly facilitate the development of new radiopharmaceuticals and their preclinical evaluation while – working in collaboration with the Department of Nuclear Medicine at the Mainz University Medical Center – we will be able to markedly expedite their future application in patient diagnosis."
There are additional benefits to be expected through interdisciplinary joint projects in which the areas of nuclear chemistry, pharmaceutical sciences, organic chemistry, and nuclear medicine at JGU will collaborate with regard to the development and evaluation of new PET radiopharmaceuticals, in some cases also with external institutions such as the Department of Psychiatry, Psychotherapy, and Psychosomatics at RWTH Aachen and the Mainz-based Max Planck Institute for Polymer Research.
Installation of the cyclotron on the campus of Johannes Gutenberg University Mainz
photo/©: Heinz-Martin Schmidt
Installment of a cyclotron door into the newly constructed cyclotron building
photo/©: Heinz-Martin Schmidt
(fltr) Professor Tobias Reich (Managing Director of the Institute of Nuclear Chemistry), Professor Norbert Trautmann (Institute of Nuclear Chemistry), Dr. Waltraud Kreutz-Gers (Chancellor of Johannes Gutenberg University Mainz), Professor Georg Krausch (President of Johannes Gutenberg University Mainz), and Professor Frank Rösch (Institute of Nuclear Chemistry) observing the installation of the new cyclotron
Professor Dr. Frank Rösch
Institute of Nuclear Chemistry
Johannes Gutenberg University Mainz (JGU)
55099 Mainz, GERMANY
phone +49 6131 39-25302
fax +49 6131 39-24692
http://www.kernchemie.uni-mainz.de – Institute of Nuclear Chemistry
http://www.uni-mainz.de/presse/19663_ENG_HTML.php – press release "German Research Foundation, Rhineland-Palatinate, and Mainz University invest more than
EUR 2 million in a cyclotron and its building complex" (19 October 2015)
http://www.uni-mainz.de/presse/20010_ENG_HTML.php - press release ;
http://www.kernchemie.uni-mainz.de/eng/index.php - Institute of Nuclear Chemistry ;
http://www.uni-mainz.de/presse/19663_ENG_HTML.php - press release "German Research Foundation, Rhineland-Palatinate, and Mainz University invest more than EUR 2 million in a cyclotron and its building complex" (19 Oct. 2015)
Petra Giegerich | idw - Informationsdienst Wissenschaft
Turning carbon dioxide into liquid fuel
06.08.2020 | DOE/Argonne National Laboratory
Tellurium makes the difference
06.08.2020 | Friedrich-Schiller-Universität Jena
Scientists at the Fraunhofer Institute for Laser Technology ILT have come up with a striking new addition to contact stamping technologies in the ERDF research project ScanCut. In collaboration with industry partners from North Rhine-Westphalia, the Aachen-based team of researchers developed a hybrid manufacturing process for the laser cutting of thin-walled metal strips. This new process makes it possible to fabricate even the tiniest details of contact parts in an eco-friendly, high-precision and efficient manner.
Plug connectors are tiny and, at first glance, unremarkable – yet modern vehicles would be unable to function without them. Several thousand plug connectors...
An international research team has found a new approach that may be able to reduce bone loss in osteoporosis and maintain bone health.
Osteoporosis is the most common age-related bone disease which affects hundreds of millions of individuals worldwide. It is estimated that one in three women...
Traditional single-cell sequencing methods help to reveal insights about cellular differences and functions - but they do this with static snapshots only...
“Core-shell” clusters pave the way for new efficient nanomaterials that make catalysts, magnetic and laser sensors or measuring devices for detecting electromagnetic radiation more efficient.
Whether in innovative high-tech materials, more powerful computer chips, pharmaceuticals or in the field of renewable energies, nanoparticles – smallest...
An international research team with Prof. Cornelia Denz from the Institute of Applied Physics at the University of Münster develop for the first time light fields using caustics that do not change during propagation. With the new method, the physicists cleverly exploit light structures that can be seen in rainbows or when light is transmitted through drinking glasses.
Modern applications as high resolution microsopy or micro- or nanoscale material processing require customized laser beams that do not change during...
23.07.2020 | Event News
21.07.2020 | Event News
07.07.2020 | Event News
06.08.2020 | Earth Sciences
06.08.2020 | Power and Electrical Engineering
06.08.2020 | Life Sciences