Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

LSUHSC research discoveries shed light on common STI

02.04.2013
Research led by David H. Martin, MD, Professor and Chief of Infectious Diseases at LSU Health Sciences Center New Orleans, has found that a common sexually transmitted infection-causing parasite "cultivates" bacteria beneficial to it, changing thinking about which comes first–infection or bacteria. The researchers also discovered a previously unknown species of these bacteria.

The research was published ahead of print online in Advance Access in the Journal of Infectious Diseases, and was published online April 2, 2013 in Research Highlights in Nature Reviews Urology.

Trichomonas vaginalis is a parasite and is a common sexually transmitted infection (STI) in women where it causes vaginal discharge, a higher rate of premature deliveries, and greater susceptibility to infection with the AIDS virus. Many women have this infection and do not know it.

It is known that a change in vaginal bacteria causes a problem known as bacterial vaginosis, and women with this condition are at increased risk of acquiring a trichomonas infection. The researchers wondered if, among women with bacterial vaginosis, there were unique bacterial communities which would make women more susceptible to infection with trichomonas.

"We discovered that there are two unique bacterial communities that are very strongly associated with trichomonas infection," notes Dr. Martin. "In part what is unique about these communities is high concentrations of bacteria known as mycoplasmas. In fact one of these is a completely unknown bacterium which we have named Mnola because it is a mycoplasma discovered in NOLA."

The mycoplasma associated with the other unique bacterial community is Mycoplasma hominis, a well known bacterial pathogen. The data indicate that women with trichomonas and this unique bacterial community suffer from worse disease than the other trichomonas-infected women. They have greater amounts of discharge and redness of the vaginal wall.

"We think that this group might also be at especially high risk for infection with HIV," adds Dr. Martin.

An especially interesting result of this research is that the evidence suggests that the trichomonas parasite is responsible in some way for the appearance these unique mycoplasma dominated bacterial communities.

"So instead of these unique communities predisposing a woman to infection as originally thought, we now believe that trichomonas takes on the role of a farmer in the vaginal environment by cultivating bacterial communities that are in some way beneficial to itself. Proving this hypothesis and figuring out how these bacteria interact with trichomonas will be the subject of future research," concludes Dr. Martin.

Other members of the LSUHSC research team included Marcela Zozaya, Rebecca Lillis,

M. Jacques Nsuami, and Michael J. Ferris from the Section of Infectious Diseases in the Department of Medicine, the Department of Microbiology, Immunology & Parasitology, the Department of Pediatrics, and the Research Institute for Children.

The research was supported by grants from the National Institute of Allergy and Infectious Diseases and the Louisiana Board of Regents.

LSU Health Sciences Center New Orleans educates Louisiana's health care professionals. The state's academic health leader, LSUHSC New Orleans consists of a School of Medicine, the state's only School of Dentistry, Louisiana's only public School of Public Health, Schools of Allied Health Professions and Graduate Studies, and the only School of Nursing within an academic health center in the State of Louisiana. To learn more, visit http://www.lsuhsc.edu and http://www.twitter.com/LSUHSCHealth.

Leslie Capo | EurekAlert!
Further information:
http://www.lsuhsc.edu

More articles from Life Sciences:

nachricht Scientists uncover the role of a protein in production & survival of myelin-forming cells
19.07.2018 | Advanced Science Research Center, GC/CUNY

nachricht NYSCF researchers develop novel bioengineering technique for personalized bone grafts
18.07.2018 | New York Stem Cell Foundation

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Future electronic components to be printed like newspapers

A new manufacturing technique uses a process similar to newspaper printing to form smoother and more flexible metals for making ultrafast electronic devices.

The low-cost process, developed by Purdue University researchers, combines tools already used in industry for manufacturing metals on a large scale, but uses...

Im Focus: First evidence on the source of extragalactic particles

For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.

To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...

Im Focus: Magnetic vortices: Two independent magnetic skyrmion phases discovered in a single material

For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.

Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...

Im Focus: Breaking the bond: To take part or not?

Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.

A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...

Im Focus: New 2D Spectroscopy Methods

Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.

"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Leading experts in Diabetes, Metabolism and Biomedical Engineering discuss Precision Medicine

13.07.2018 | Event News

Conference on Laser Polishing – LaP: Fine Tuning for Surfaces

12.07.2018 | Event News

11th European Wood-based Panel Symposium 2018: Meeting point for the wood-based materials industry

03.07.2018 | Event News

 
Latest News

A smart safe rechargeable zinc ion battery based on sol-gel transition electrolytes

20.07.2018 | Power and Electrical Engineering

Reversing cause and effect is no trouble for quantum computers

20.07.2018 | Information Technology

Princeton-UPenn research team finds physics treasure hidden in a wallpaper pattern

20.07.2018 | Materials Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>