A new Research Training Group aims to decode the complex structure of peptides. The German Research Foundation is to provide EUR 4.5 million in funding for the research
TU Berlin is to act as host university of the new “Bioactive Peptides – Innovative Aspects of Synthesis and Biosynthesis” Research Training Group (RTG2473/1).
The German Research Foundation (DFG) approved the funding of this new Research Training Group on 9 November 2018. Spokesperson will be Professor Roderich Süssmuth. The Research Training Group will conduct research in the areas of molecular biology, biochemistry, biological chemistry and bioanalytics.
Professor Süssmuth has been Rudolf Wiechert Professor of Biological Chemistry at TU Berlin since 2004, where he also heads the Chair of Biological Chemistry. The German Research Foundation will provide the Research Training Group with funding of approximately EUR 4.5 million over a period of four and a half years from 1 April 2019 until 30 September 2023. The German Research Foundation has approved a total of 15 new Research Training Groups.
In biological chemistry, biochemistry and medicinal research, natural and synthetic peptides play a significant role in the development of tools, as products of novel biosynthetic pathways and as binding partners for molecular target structures in drug search.
The various functions of peptides are in large determined by their partially complex molecular structure and their spatial folding. Research on these characteristics will form an essential part of the Research Training Group’s work.
The investigation of mechanisms of biosynthesis and their modes of actions with biological target structures represent further challenges of modern peptide research. These complex issues form the central focus of the new “Bioactive Peptides” Research Training Group.
Peptides are mostly chain-like molecules made up of between two and 100 amino acids - the building blocks of every protein in a cell. Chains made up of more than 100 amino acids are classified as proteins. As such, peptides, which are enormously diverse, can be seen as the “little brothers and sisters” of proteins. In living organisms, they not only function as biocatalysts, semiochemicals and transport substances, but also as storage materials.
Doctoral students participating in the Research Training Group will focus on peptide research via a didactically structured curriculum based on a thorough and interdisciplinary approach. The curriculum’s areas of focus are molecular biology/biochemistry, synthetic chemistry, and bioanalytics/ structural biology.
“In recent years peptide research has achieved a particular importance in academic and industrial research. Consequently, there is a growing need for knowledgeable researchers with excellent academic backgrounds who understand and can speak the language of other disciplines,” Professor Süssmuth explains.
In addition to TU Berlin, the participating institutions in the Research Training Group are Freie Universität Berlin, Humboldt Universität zu Berlin and the Forschungsinstitut für Molekulare Pharmakologie (FMP) in Berlin-Buch. The teaching staff will be supplemented by contributions from internationally renowned peptide researchers from academia and industry.
High-profile senior scientists will act as advisers within the Research Training Group. Professor Süssmuth sees the undertaking overall as a sustainable project which all participating research groups look forward to being involved in.
For further information please contact:
Prof. Dr. Roderich Süssmuth
Chair of Biological Chemistry
Stefanie Terp | idw - Informationsdienst Wissenschaft
Small but versatile; key players in the marine nitrogen cycle can utilize cyanate and urea
10.12.2018 | Max-Planck-Institut für Marine Mikrobiologie
Carnegie Mellon researchers probe hydrogen bonds using new technique
10.12.2018 | Carnegie Mellon University
What if a sensor sensing a thing could be part of the thing itself? Rice University engineers believe they have a two-dimensional solution to do just that.
Rice engineers led by materials scientists Pulickel Ajayan and Jun Lou have developed a method to make atom-flat sensors that seamlessly integrate with devices...
Scientists at the University of Stuttgart and the Karlsruhe Institute of Technology (KIT) succeed in important further development on the way to quantum Computers.
Quantum computers one day should be able to solve certain computing problems much faster than a classical computer. One of the most promising approaches is...
New Project SNAPSTER: Novel luminescent materials by encapsulating phosphorescent metal clusters with organic liquid crystals
Nowadays energy conversion in lighting and optoelectronic devices requires the use of rare earth oxides.
Scientists have discovered the first synthetic material that becomes thicker - at the molecular level - as it is stretched.
Researchers led by Dr Devesh Mistry from the University of Leeds discovered a new non-porous material that has unique and inherent "auxetic" stretching...
Scientists from the Theory Department of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science (CFEL) in Hamburg have shown through theoretical calculations and computer simulations that the force between electrons and lattice distortions in an atomically thin two-dimensional superconductor can be controlled with virtual photons. This could aid the development of new superconductors for energy-saving devices and many other technical applications.
The vacuum is not empty. It may sound like magic to laypeople but it has occupied physicists since the birth of quantum mechanics.
10.12.2018 | Event News
06.12.2018 | Event News
03.12.2018 | Event News
10.12.2018 | Life Sciences
10.12.2018 | Physics and Astronomy
10.12.2018 | Life Sciences