Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Genomewide mapping reveals developmental and environmental impacts

17.08.2011
Complex traits that help plants adapt to environmental challenges are likely influenced by variations in thousands of genes that are affected by both the plant's growth and the external environment, reports a team of researchers at the University of California, Davis.

The findings were revealed by a genomewide association mapping of the defense metabolism in Arabidopsis thaliana, a common research plant. The researchers, led by UC Davis plant scientist Daniel Kliebenstein, report the study results today, Aug. 16, in the online journal PLoS Genetics.

In the study, Kliebenstein and colleagues measured glucosinolates (GSL), a key class of compounds that the plant produces to protect against insect attacks and disease-causing organisms. The researchers measured the compound in two developmental stages — at two days and 35 days after germination. They also sampled plant tissues that were either treated or not treated with silver nitrate, mimicking environmental damage caused by a pest.

"We showed that both external and internal environments altered the identified genes so significantly that using plant tissues from different developmental stages, or that were treated with the silver nitrate, led to the identification of very different gene sets for particular traits," Kliebenstein said.

The group noted that the developmental stage of the plant had three times as much influence as the environment on the genes they identified.

Because the genomewide association mapping identified so many different genes as potentially responsible for traits associated with GSL metabolism, the researchers developed a new process for winnowing candidate genes. The process analyzes overlapping datasets of genomic information to filter out true-positive gene identifications.

Genomewide association mapping involves rapidly scanning markers across entire genomes to find genetic variations associated with a particular trait, condition or disease. The approach has been used to study complex human diseases such as asthma and diabetes.

The researchers hope that the new two-pronged approach to genomewide association can be applied to any plant and animal species.

In addition to Kliebenstein, the UC Davis research team included Eva Chan, a former UC Davis postdoctoral fellow now working at Monsanto Company in Woodland, Calif.; plant science graduate student Jason Corwin; and plant science postdoctoral fellow Bindu Joseph.

The study was funded by the National Science Foundation.

Patricia Bailey | EurekAlert!
Further information:
http://www.ucdavis.edu

More articles from Life Sciences:

nachricht Chips, light and coding moves the front line in beating bacteria
16.08.2018 | Okinawa Institute of Science and Technology (OIST) Graduate University

nachricht Protein droplets keep neurons at the ready and immune system in balance
16.08.2018 | Howard Hughes Medical Institute

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Unraveling the nature of 'whistlers' from space in the lab

A new study sheds light on how ultralow frequency radio waves and plasmas interact

Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...

Im Focus: New interactive machine learning tool makes car designs more aerodynamic

Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.

When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...

Im Focus: Robots as 'pump attendants': TU Graz develops robot-controlled rapid charging system for e-vehicles

Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.

Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....

Im Focus: The “TRiC” to folding actin

Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.

Actin is the most abundant protein in highly developed cells and has diverse functions in processes like cell stabilization, cell division and muscle...

Im Focus: Lining up surprising behaviors of superconductor with one of the world's strongest magnets

Scientists have discovered that the electrical resistance of a copper-oxide compound depends on the magnetic field in a very unusual way -- a finding that could help direct the search for materials that can perfectly conduct electricity at room temperatur

What happens when really powerful magnets--capable of producing magnetic fields nearly two million times stronger than Earth's--are applied to materials that...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Within reach of the Universe

08.08.2018 | Event News

A journey through the history of microscopy – new exhibition opens at the MDC

27.07.2018 | Event News

2018 Work Research Conference

25.07.2018 | Event News

 
Latest News

Diving robots find Antarctic seas exhale surprising amounts of carbon dioxide in winter

16.08.2018 | Earth Sciences

Protein droplets keep neurons at the ready and immune system in balance

16.08.2018 | Life Sciences

3D inks that can be erased selectively

16.08.2018 | Materials Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>