Prof. Eugene “Gene” Myers, one of the pioneers in bioinformatics, is affiliated with the group as a mentor. Together with his laboratory at the Max Planck Center for Systems Biology in Dresden, the junior group will decipher and compare the genetic codes of several flatworm species.
Flatworms are masters of regeneration, and are, therefore, interesting for scientists: If they are cut in two pieces, each half will develop into a new worm. By comparing the genetic material, researchers hope to gain new insights into regeneration of tissue that could have a huge impact on medicine.A new junior research group for Computational Biology (CBI) has been established at Heidelberg Institute for Theoretical Studies (HITS). It complements the work of the other six research groups, which carry out basic research in different fields of science. The focus lies on the processing and structuring of large data volumes. The leader of the new group is Dr. Siegfried Schloissnig, a 33-year-old Computer Scientist with a Doctorate in Human Biology, who previously worked as a PostDoc at the European Molecular Biology Laboratory (EMBL). A PostDoc and two PhD students will work under his leadership in Heidelberg.
New approaches to the de novo assemblyThe new junior research group at HITS will also work on these objectives in collaboration with Gene Myers’ laboratory in Dresden and the recently established Dresden Genome Center. Together with his group, Siegfried Schloissnig will develop new approaches to the so-called de novo assembly, which is the reconstruction of genome sequences by means of DNA sequencers and bioinformatic methods. In the course of sequencing by standard methods, DNA is copied multiple times. These copies are randomly split up into numerous small fragments. These fragments are examined for overlaps by means of bioinformatic methods and are subsequently reassembled. The smaller the fragments and the more complex the genome of interest, the more complicated is the problem. The situation becomes even more difficult, when no comparable genome is available and researchers have to assemble the genome de novo, i.e. anew. This is exactly the case with flatworms, whose genetic codes the HITS junior group plans to decipher.
Dr. Peter Saueressig | idw
Microscope measures muscle weakness
16.11.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg
Good preparation is half the digestion
16.11.2018 | Max-Planck-Institut für Stoffwechselforschung
Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.
Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
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16.11.2018 | Life Sciences