As part of the German government’s High-Tech-Strategy 2025, the Federal Ministry of Education and Research (BMBF) is funding an interdisciplinary research group that aims to use an innovative circuit technology to solve a central problem of genetic investigation of human single cells. Medical professionals hope that such research will drastically improve the diagnosis and therapy of many serious diseases and enable the treatment of or even cure for cancer and immune diseases, for which there are currently no suitable methods available.
However, this will require molecular analysis systems that can examine hundreds or thousands of these cells individually and simultaneously. Current technology does not allow such analyses.
Scientists in Dresden would therefore like to use chemo-fluidic circuits developed at the “Center for Advancing Electronics Dresden” cluster.
These are based on chemical transistors, which, analogous to microelectronics, make it possible to combine complete information-processing systems on a single chip.
However, they do not control electrical currents, but rather the fluid currents containing the human cells, which are to be examined. And they themselves are directed through the chemicals and liquids necessary for the analysis.
The researchers strive to build integrated circuits that, owing to the combination of thousands chemical transistors on a chip, are able to independently and simultaneously conduct complex analysis procedures on hundreds or thousands of individual human cells.
Initially, the scientists will focus on the development of chemical chips for the diagnosis of a special type of white blood cell cancer (acute myeloid leukaemia), for which therapy could be fundamentally improved if successful. At a later stage, they hope to develop circuits for the treatment of other diseases.
Financing by the VIP+ Programme of the BMBF:
With the High-Tech-Strategy 2025 “Research and Innovation for People”, the Federal Government has set itself the goal of identifying the diverse application potentials of excellent research even more quickly and effectively, and of making them available to industry and society.
To achieve this, the bridge between academic research and it’s commercial exploitation or societal application must be further strengthened. The BMBF funding measure “Validation of the technological and societal innovation potential of scientific research – VIP+” addresses this issue and supports researchers in systematically validating research results and in opening up areas of application.
Prof. Dr. Andreas Richter
Technische Universität Dresden
Faculty of Electrical and Computer Engineering
Institute for Semiconductors and Microsystems
Tel.: +49 351 463 36336
Prof. Dr. Mario Menschikowski
Carl Gustav Carus University Hospital Dresden
Institute for Clinical Chemistry and Laboratory Medicine
Tel.: +49 351 458-2634
Katrin Presberger | Technische Universität Dresden
Towards better anti-cancer drugs: New insights into CDK8, an important human oncogene
28.01.2020 | Universität Bayreuth
Unique centromere type discovered in the European dodder
28.01.2020 | Leibniz Institute of Plant Genetics and Crop Plant Research
Researchers from Dresden and Osaka present the first fully integrated flexible electronics made of magnetic sensors and organic circuits which opens the path towards the development of electronic skin.
Human skin is a fascinating and multifunctional organ with unique properties originating from its flexible and compliant nature. It allows for interfacing with...
Researchers of the Carl Gustav Carus University Hospital Dresden at the National Center for Tumor Diseases Dresden (NCT/UCC), together with an international...
A Duke University research team has identified a new function of a gene called huntingtin, a mutation of which underlies the progressive neurodegenerative...
For years, a new synthesis method has been developed at TU Wien (Vienna) to unlock the secrets of "strange metals". Now a breakthrough has been achieved. The results have been published in "Science".
Superconductors allow electrical current to flow without any resistance - but only below a certain critical temperature. Many materials have to be cooled down...
KIT researchers develop novel composites of DNA, silica particles, and carbon nanotubes -- Properties can be tailored to various applications
Using DNA, smallest silica particles, and carbon nanotubes, researchers of Karlsruhe Institute of Technology (KIT) developed novel programmable materials....
16.01.2020 | Event News
15.01.2020 | Event News
07.01.2020 | Event News
28.01.2020 | Life Sciences
28.01.2020 | Materials Sciences
28.01.2020 | Health and Medicine