Over the last few decades there has been an explosion in the discovery of biomarkers for diagnosis, disease monitoring, and prognostic evaluation. In the April issue of Translational Research, entitled "Biomarkers: New Tools of Modern Medicine," an international group of medical experts explores the promise and challenges of biomarker discovery and highlights the latest advances in the use of biomarkers in various diseases.
In a commentary introducing this single-topic issue, Nikolaos G. Frangogiannis, MD, The Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, notes, "Although advanced technologies and hypothesis-driven approaches fueled by the '-omics' revolution continue to provide clinicians and researchers with an expanding list of candidate markers, very few are likely to survive the test as useful clinical tools."
Given the complexity of most common conditions, Dr. Frangogiannis says that multimarker approaches assessing the major aspects of the pathophysiology of the disease may be needed. "Development and implementation of such ambitious efforts will undoubtedly face many challenges, but may eventually fulfill the visionary goal of personalized medicine," he concludes.
HIGHLIGHTS:Biomarkers: Hopes and Challenges in the Path from Discovery to Clinical Practice
These articles appear in Translational Research, The Journal of Laboratory and Clinical Medicine, Volume 159, Issue 4 (April 2012) entitled "Biomarkers: New Tools of Modern Medicine," published by Elsevier.
Andrea Allison-Williams | EurekAlert!
Molecular motors run in unison in a metal-organic framework
20.03.2019 | University of Groningen
Active substance from plant slows down aggressive eye cancer
20.03.2019 | Rheinische Friedrich-Wilhelms-Universität Bonn
Due to the special arrangement of its molecules, a new coating made of corn starch is able to repair small scratches by itself through heat: The cross-linking via ring-shaped molecules makes the material mobile, so that it compensates for the scratches and these disappear again.
Superficial micro-scratches on the car body or on other high-gloss surfaces are harmless, but annoying. Especially in the luxury segment such surfaces are...
The Potsdam Echelle Polarimetric and Spectroscopic Instrument (PEPSI) at the Large Binocular Telescope (LBT) in Arizona released its first image of the surface magnetic field of another star. In a paper in the European journal Astronomy & Astrophysics, the PEPSI team presents a Zeeman- Doppler-Image of the surface of the magnetically active star II Pegasi.
A special technique allows astronomers to resolve the surfaces of faraway stars. Those are otherwise only seen as point sources, even in the largest telescopes...
Researchers at Chalmers University of Technology and the University of Gothenburg, Sweden, have proposed a way to create a completely new source of radiation. Ultra-intense light pulses consist of the motion of a single wave and can be described as a tsunami of light. The strong wave can be used to study interactions between matter and light in a unique way. Their research is now published in the scientific journal Physical Review Letters.
"This source of radiation lets us look at reality through a new angle - it is like twisting a mirror and discovering something completely different," says...
New research group at the University of Jena combines theory and experiment to demonstrate for the first time certain physical processes in a quantum vacuum
For most people, a vacuum is an empty space. Quantum physics, on the other hand, assumes that even in this lowest-energy state, particles and antiparticles...
Physicists in the EPic Lab at University of Sussex make crucial development in global race to develop a portable atomic clock
Scientists in the Emergent Photonics Lab (EPic Lab) at the University of Sussex have made a breakthrough to a crucial element of an atomic clock - devices...
11.03.2019 | Event News
01.03.2019 | Event News
28.02.2019 | Event News
20.03.2019 | Life Sciences
20.03.2019 | Life Sciences
20.03.2019 | Trade Fair News