Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

MelTec Forms Alliance with Fraunhofer Institute FIT

21.01.2003


Next-Generation IT Platform for Topological Proteomics to be Created



MelTec GmbH and the Fraunhofer Institute for Applied Information Technology FIT today signed a collaboration agreement to develop an information technology platform for the management and interpretation of high-throughput experiments analysing protein networks of whole cells in situ, also known as topological proteomics or toponomics. MelTec continuously generates large data sets to decipher the toponome of cells and tissues by tracing out and interpreting the context of proteins in cells.

Under this agreement, FIT and MelTec will develop new software-based approaches to analyse and visualise protein networks, and then correlate that data with results from in-vitro and in-vivo experiments. Using MelTec’s robotic toponomics imaging technology in combination with FIT’s image management and proteomics software, they will create a bioinformatics platform for the systematic interpretation of these vast protein networks. The system will rapidly produce high quality results for understanding how proteins impact a drug’s effectiveness.


"Our Topological Proteomics technologies combine cell biology and bio-mathematical tools to visualize 3-Dimensional protein-networks at the cellular and subcellular level," said Walter Schubert, M.D., Founder and Chief Executive Officer of MelTec. "This new system has the potential to become a key technology that paves the way for a more systematic approach to understanding disease pathology and treatment, by looking at how protein networks in cells determine cellular function. The alliance with FIT will accelerate our discovery program."

"Large-scale image-based experiments require advanced information management approaches that combine storage, processing and interactive exploration capabilities," said Prof. Dr. Thomas Berlage, Institute Director at the Fraunhofer Institute for Applied Information Technology FIT. "Our alliance will allow us to create an integrated environment that enables biologists to quickly identify and validate functional aspects of living cells."

About MelTec
MelTec GmbH is a privately held biotechnology company specializing in using topological proteomics to identify mechanisms underlying disease pathology, drug targets and to prioritize lead compounds focused on immune-mediated disease, neurological disorders, cancer, and arteriosclerosis. MelTec’s proprietary robotic imaging technology, MELK (Multi-Epitope-Ligand-Kartographie), performs completely automated proteomic characterization of single cells, for hundreds of proteins simultaneously, thus identifying the proteomic fingerprint, or the topology, of individual cells, such as lymphocytes. Using its technology, MelTec believes that it can greatly accelerate pre-clinical research in the drug development process, and has already identified new targets and lead compounds in amyotrophic lateral sclerosis (ALS, Lou Gehrig’s Disease) and cancer.

About Fraunhofer FIT
The Fraunhofer Institute for Applied Information Technology FIT is one of the 56 institutes of the Fraunhofer Society in Germany. FIT investigates user-oriented information and cooperation systems, focusing on the interaction of actual work practices, organizational structure and processes, in close cooperation with its clients from industry and public administration. One major application area is life science, where diagnostic and therapeutic approaches are increasingly relying on image-based technologies and integrated computerized approaches. FIT is pursuing research on novel software systems that address the anatomical, physiological and molecular levels of life.


Alex Deeg | idw
Further information:
http://www.fit.fraunhofer.de/
http://www.meltec.de/

More articles from Interdisciplinary Research:

nachricht The Internet of Things: TU Graz researchers increase the dependability of smart systems
18.02.2019 | Technische Universität Graz

nachricht Stanford researchers create a wireless, battery-free, biodegradable blood flow sensor
09.01.2019 | Stanford University

All articles from Interdisciplinary Research >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Stellar cartography

The Potsdam Echelle Polarimetric and Spectroscopic Instrument (PEPSI) at the Large Binocular Telescope (LBT) in Arizona released its first image of the surface magnetic field of another star. In a paper in the European journal Astronomy & Astrophysics, the PEPSI team presents a Zeeman- Doppler-Image of the surface of the magnetically active star II Pegasi.

A special technique allows astronomers to resolve the surfaces of faraway stars. Those are otherwise only seen as point sources, even in the largest telescopes...

Im Focus: Heading towards a tsunami of light

Researchers at Chalmers University of Technology and the University of Gothenburg, Sweden, have proposed a way to create a completely new source of radiation. Ultra-intense light pulses consist of the motion of a single wave and can be described as a tsunami of light. The strong wave can be used to study interactions between matter and light in a unique way. Their research is now published in the scientific journal Physical Review Letters.

"This source of radiation lets us look at reality through a new angle - it is like twisting a mirror and discovering something completely different," says...

Im Focus: Revealing the secret of the vacuum for the first time

New research group at the University of Jena combines theory and experiment to demonstrate for the first time certain physical processes in a quantum vacuum

For most people, a vacuum is an empty space. Quantum physics, on the other hand, assumes that even in this lowest-energy state, particles and antiparticles...

Im Focus: Sussex scientists one step closer to a clock that could replace GPS and Galileo

Physicists in the EPic Lab at University of Sussex make crucial development in global race to develop a portable atomic clock

Scientists in the Emergent Photonics Lab (EPic Lab) at the University of Sussex have made a breakthrough to a crucial element of an atomic clock - devices...

Im Focus: Sensing shakes

A new way to sense earthquakes could help improve early warning systems

Every year earthquakes worldwide claim hundreds or even thousands of lives. Forewarning allows people to head for safety and a matter of seconds could spell...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

International Modelica Conference with 330 visitors from 21 countries at OTH Regensburg

11.03.2019 | Event News

Selection Completed: 580 Young Scientists from 88 Countries at the Lindau Nobel Laureate Meeting

01.03.2019 | Event News

LightMAT 2019 – 3rd International Conference on Light Materials – Science and Technology

28.02.2019 | Event News

 
Latest News

Levitating objects with light

19.03.2019 | Physics and Astronomy

New technique for in-cell distance determination

19.03.2019 | Life Sciences

Stellar cartography

19.03.2019 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>