The German Centre for Cardiovascular Research (DZHK) is hosting a global meeting of world leading scientists to answer the question: How can the benefits of medical research reach the patient?
DZHK Conference on Translational Medicine in Berlin, 9th to 10th January 2019
Scientists and healthcare professionals all over the world ask themselves this question as diseases like dementia, cardiovascular diseases and cancer continue to pose an increasingly significant challenge in our ever-ageing society.
Translation is the process of bringing new research into routine medical practice, but this usually happens too rarely and too slowly. The demands on modern medicine have also changed as we improve treatments and strive to offer personalised medicine. Big data and artificial intelligence are now finding their way into all areas of research and health care.
To further complicate matters, the painstaking process of bringing research to true patient benefit can involve collaborations across different disciplines and sectors - between researchers and doctors, computational scientists and industry leaders, and even regulatory authorities, health services and many more.
“There is no sure formula for successful translation, but we are all learning from each other” says DZHK Board Chairman Thomas Eschenhagen. The conference will cover not only cardiovascular research but also showcase examples of successful translation from other disease areas.
Michaela Sharpe from the Catapult Programme in London will report on how they have built a network that encourages UK businesses, scientists and engineers to work together, to bring medical innovation onto the market.
The Mainz-based researcher and biotech entrepreneur Ugur Sahin will speak about his new cancer therapy, which is the result of years of research and development, showing promise in treating melanoma. The therapy reprogrammes a patient’s immune cells to recognise the individual characteristics of cancer cells and destroy them. Researchers and authorities are breaking new ground when it comes to the authorisation of such personalised medicine, where conventional clinical trials are not suitable.
“Successes, like those of Ugur Sahin, encourage us translational researchers and show that it is worth thinking in new ways” states Eschenhagen. Yet for him, it is also important to convey a realistic picture to early career researchers. According to him, translation is not synonymous with quick success.
Instead, having a lot of staying power and a strong network is required. The DZHK is one of six German Centres for Health Research (DZG), the founding of which was initiated by the German Federal Government. Each of the centres unites experts on a widespread disease from all over Germany with the aim of accelerating translation.
Pierluigi Nicotera, Scientific Director of the German Center for Neurodegenerative Diseases (DZNE), will show how a new computer system – so-called Memory-Driven Computing – will contribute to new findings in the area of genome research and image analysis, with particular emphasis on neurodegenerative diseases.
In the area of cardiovascular research, DZHK researchers have made major progress in the last three years with artificial heart tissue grown from stem cells. Tissues of this kind are required because damaged heart cells cannot repair themselves after a heart attack. At the conference, projects will be introduced that are preparing their first trials in humans.
“The basis for successful translation is still good science”, says Eschenhagen with conviction. According to him, translation needs both strong basic research and programmes that purposefully transfer the results of this research into application.
2nd DZHK Conference on Translational Medicine
9th to 10th January 2019, Berlin, Langenbeck-Virchow-Haus
Programme and registration:
The official language of the conference is English.
Christine Vollgraf | idw - Informationsdienst Wissenschaft
Dresden Nexus Conference 2020: Same Time, Virtual Format, Registration Opened
19.05.2020 | Leibniz-Institut für ökologische Raumentwicklung e. V.
Aachen Machine Tool Colloquium AWK'21 will take place on June 10 and 11, 2021
07.04.2020 | Fraunhofer-Institut für Produktionstechnologie IPT
An analysis of more than 200,000 spiral galaxies has revealed unexpected links between spin directions of galaxies, and the structure formed by these links...
Two prominent X-ray emission lines of highly charged iron have puzzled astrophysicists for decades: their measured and calculated brightness ratios always disagree. This hinders good determinations of plasma temperatures and densities. New, careful high-precision measurements, together with top-level calculations now exclude all hitherto proposed explanations for this discrepancy, and thus deepen the problem.
Hot astrophysical plasmas fill the intergalactic space, and brightly shine in stellar coronae, active galactic nuclei, and supernova remnants. They contain...
In living cells, enzymes drive biochemical metabolic processes enabling reactions to take place efficiently. It is this very ability which allows them to be used as catalysts in biotechnology, for example to create chemical products such as pharmaceutics. Researchers now identified an enzyme that, when illuminated with blue light, becomes catalytically active and initiates a reaction that was previously unknown in enzymatics. The study was published in "Nature Communications".
Enzymes: they are the central drivers for biochemical metabolic processes in every living cell, enabling reactions to take place efficiently. It is this very...
Early detection of tumors is extremely important in treating cancer. A new technique developed by researchers at the University of California, Davis offers a significant advance in using magnetic resonance imaging to pick out even very small tumors from normal tissue. The work is published May 25 in the journal Nature Nanotechnology.
researchers at the University of California, Davis offers a significant advance in using magnetic resonance imaging to pick out even very small tumors from...
Microelectronics as a key technology enables numerous innovations in the field of intelligent medical technology. The Fraunhofer Institute for Biomedical Engineering IBMT coordinates the BMBF cooperative project "I-call" realizing the first electronic system for ultrasound-based, safe and interference-resistant data transmission between implants in the human body.
When microelectronic systems are used for medical applications, they have to meet high requirements in terms of biocompatibility, reliability, energy...
19.05.2020 | Event News
07.04.2020 | Event News
06.04.2020 | Event News
03.06.2020 | Medical Engineering
03.06.2020 | Physics and Astronomy
03.06.2020 | Physics and Astronomy