Swansea University ecologist Dr Patricia Lee has won a British Ecological Society (BES) grant to unlock the secrets of the millions of eggs held in museum collections worldwide.
The bird collection at Londons Natural History Museum alone includes more than a million skins and eggs, collected over the past 200 years and representing 95% of all known bird species. While the skins have proved a good source of DNA and have been widely used by scientists to study many aspects of bird biology, using the eggs for similar research has so far been problematic.
According to Lee: “Unlike bird skin specimens, eggs can be difficult to identify on appearance because many bird species produce essentially identical eggs, and until recently it was not known if DNA could be obtained from blown eggs. Other work involving the Natural History Museums collections has now demonstrated that enough DNA can sometimes be extracted from the residual dry membranes of duck eggs to identify the species of bird that the egg came from. This project will compare the quality and quantity of DNA that can be extracted from archive eggs with the DNA from skins. This will allow us to find out whether or not it is feasible to use DNA from archive eggs and find the most appropriate method of extracting the DNA.”
Becky Allen | alfa
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Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.
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