Study in Environmental Health Perspectives Also Finds Interference with Sex Hormone Synthesis
Male school children exposed to the pesticide endosulfan showed delayed sexual maturity compared with similar children who were not exposed, according to a study published today in the December issue of the peer-reviewed journal Environmental Health Perspectives (EHP). Endosulfan also appears to interfere with sex hormone synthesis, according to results of the study of males aged 10-19 years in a community of cashew plantations in northern Kerala, India. Although endosulfan is no longer made in the United States, an estimated 1.4-2.2 million pounds are used in the United States on crops including squash, pecans, and strawberries.
Researchers evaluated 117 boys in a village where endosulfan has been aerially sprayed for more than 20 years and 90 comparable boys from a nearby village with no such exposure history. For each group, the researchers performed physical examinations and recorded clinical history, sexual maturity rating, and blood levels of various hormones. The study found a higher prevalence of congenital abnormalities related to testicular descent in the study group, but it was not statistically significant due to a small sample size.
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