Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Newly demonstrated capabilities of low-powered nanotweezers may benefit cellular-level studies

18.09.2012
Using ultra-low input power densities, researchers at the University of Illinois at Urbana-Champaign have demonstrated for the first time how low-power “optical nanotweezers” can be used to trap, manipulate, and probe nanoparticles, including fragile biological samples.

Experimental setup schematic showing laser source, microscope, and imaging detector and spectrometer. The inset illustrates the two different sample configurations that were explored; red arrows correspond to the input polarization directions and black arrows depict the propagation vector.

“We already know that plasmonic nanoantennas enhance local fields by up to several orders of magnitude, and thus, previously showed that we can use these structures with a regular CW laser source to make very good optical tweezers,” explains, Kimani Toussaint, Jr., assistant professor of mechanical science and engineering at Illinois. “This is exciting because, for the first time, we’re showing that, the near-field optical forces can be enhanced even further, without doing anything extra in terms of fabrication, but rather simply by exploiting the high-peak powers associated with using a femtosecond (fs) optical source.

“We used an average power of 50 microwatts to trap, manipulate, and probe nanoparticles. This is 100x less power than what you would get from a standard laser pointer.”

In their recent paper, “Femtosecond-pulsed plasmonic nanotweezers” published in the September 17 issue of Scientific Reports; doi:10.1038/srep00660), the researchers describe how a femtosecond-pulsed laser beam significantly augments the trapping strength of Au bowtie nanoantennas arrays (BNAs), and the first demonstration of use of femtosecond (fs) source for optical trapping with plasmonic nanotweezers.

“Our system operates at average power levels approximately three orders of magnitude lower than the expected optical damage threshold for biological structures, thereby making this technology very attractive for biological (lab-on-a-chip) applications such as cell manipulation,” added Toussaint, who is also an affiliate faculty member in the Department of Bioengineering and the Department of Electrical and Computer Engineering. “This system offers increased local diagnostic capabilities by permitting the probing of the nonlinear optical response of trapped specimens, enabling studies of in vitro fluorescent-tagged cells, or viruses using a single line for trapping and probing rather than two or more laser lines.”

"We present strong evidence that a fs source could actually augment the near-field optical forces produced by the BNAs, and most likely, other nanoantenna systems, as well. To our knowledge, this has never been demonstrated,” said Brian Roxworthy, a graduate student in Toussaint’s PROBE (Photonics Research of Bio/nano Environments) lab group and first author of the paper. According to Roxworthy, the demonstration of controlled particle fusing could be important for creating novel nanostructures, as well as for enhancing the local magnetic field response, which will be important for the field of magnetic plasmonics.

The paper also demonstrated enhancement of trap stiffness of up to 2x that of a comparable continuous-wave (CW) nanotweezers and 5x that of conventional optical tweezers that employ a fs source; successful trapping and tweezing of spherical particles ranging from 80-nm to 1.2-um in diameter, metal, dielectric, and both fluorescent and non- fluorescent particles; enhancement of two-photon fluorescent signal from trapped microparticles in comparison to the response without the presence of the BNAs; enhancement of the second-harmonic signal of ~3.5x for the combined nanoparticle-BNA system compared to the bare BNAs; and fusing of Ag nanoparticles to the BNAS.

Contact: Kimani C. Toussaint, Jr., Department of Mechanical Science & Engineering, 217/244-4088.

Kimani C. Toussaint, Jr. | EurekAlert!
Further information:
http://www.illinois.edu
http://engineering.illinois.edu/news/2012/09/17/newly-demonstrated-capabilities-low-powered-nanotweezers-may-benefit-cellular-level-

More articles from Power and Electrical Engineering:

nachricht The role of Sodium for the Enhancement of Solar Cells
17.07.2018 | Max-Planck-Institut für Eisenforschung GmbH

nachricht Behavior-influencing policies are critical for mass market success of low carbon vehicles
17.07.2018 | International Institute for Applied Systems Analysis (IIASA)

All articles from Power and Electrical Engineering >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: First evidence on the source of extragalactic particles

For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.

To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...

Im Focus: Magnetic vortices: Two independent magnetic skyrmion phases discovered in a single material

For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.

Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...

Im Focus: Breaking the bond: To take part or not?

Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.

A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...

Im Focus: New 2D Spectroscopy Methods

Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.

"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....

Im Focus: Chemical reactions in the light of ultrashort X-ray pulses from free-electron lasers

Ultra-short, high-intensity X-ray flashes open the door to the foundations of chemical reactions. Free-electron lasers generate these kinds of pulses, but there is a catch: the pulses vary in duration and energy. An international research team has now presented a solution: Using a ring of 16 detectors and a circularly polarized laser beam, they can determine both factors with attosecond accuracy.

Free-electron lasers (FELs) generate extremely short and intense X-ray flashes. Researchers can use these flashes to resolve structures with diameters on the...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Leading experts in Diabetes, Metabolism and Biomedical Engineering discuss Precision Medicine

13.07.2018 | Event News

Conference on Laser Polishing – LaP: Fine Tuning for Surfaces

12.07.2018 | Event News

11th European Wood-based Panel Symposium 2018: Meeting point for the wood-based materials industry

03.07.2018 | Event News

 
Latest News

Microscopic trampoline may help create networks of quantum computers

17.07.2018 | Information Technology

In borophene, boundaries are no barrier

17.07.2018 | Materials Sciences

The role of Sodium for the Enhancement of Solar Cells

17.07.2018 | Power and Electrical Engineering

VideoLinks
Science & Research
Overview of more VideoLinks >>>