Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

A lab-on-a-chip with moveable channels

24.03.2010
Microfluidic devices typically depend upon electrokinetic or traditional pressure methods to move microscopic amounts of fluid around a fixed microchip.

As just published as the cover story in “Lab on a Chip,” in “Virtual electrowetting channels: electronic liquid transport with continuous channel functionality,” engineering researchers at the University of Cincinnati have created a paradigm shift — and moved some tiny channels in the process.

"Virtual Electrowetting Channels" is the cover story for March.

“‘Lab on a Chip’ is the top journal in the microfluidics community, with an acceptance rate of less than one out of three,” says Ian Papautsky, one of the paper’s authors.

The field of microfluidics has been intensely investigated for nearly two decades, being traditionally explored within fixed geometries of continuous polymer or glass microchannels. None of the prior approaches was capable of creating any desired channel geometry and being able to keep that channel configuration intact without external stimulus.

With that capability, electrically induced channel functions could bridge the gap between the worlds of programmable droplet and continuous flow microfluidics.

Someone just bridged that “micromoat.”

"So here we are working on displays, and creating cutting-edge techniques at moving colored fluids around, and we nearly overlooked the possibilities in lab-on-a-chip or biomedical areas,” says Jason Heikenfeld, director of UC’s Novel Devices Laboratory and an associate professor of electrical engineering in UC’s College of Engineering and Applied Science. Heikenfeld has been making a name for himself — and UC — in the fields of photonics and electrofluidic display technology.

“This is where collaboration comes into play,” Heikenfeld continues. “Here at UC we have several internationally known experts in microfluidics and lab-on-a-chip devices. We started collaborating with one of them, Ian Papautsky, and now we find ourselves in the middle of an exciting new application space."

“In microfluidics, we typically work with either continuous flows which give us high throughputs or droplets (digital flows) that can be manipulated electrically,” says Papautsky, associate professor of electrical engineering. Papautsky is also director of UC’s BioMicroSystems Lab and director of the Micro/Nano Fabrication Engineering Research Center. “In our new collaboration with Jason Heikenfeld, we are merging these two paradigms into a programmable microfluidic system. This is especially exciting because traditionally all lab-on-a-chip devices are limited by the predefined microchannel structure. A programmable microfluidics platform would offer an ability to reconfigure microchannel structure as needed for performing a wide range of biomedical assays, from DNA analysis to immunoassays, on the same chip.”

“I am excited to see our work so well received,” Papautsky adds.

“Virtual electrowetting channels: electronic liquid transport with continuous channel functionality,” Lab on a Chip, by Manjeet Dhindsa, Jason Heikenfeld, Seyeoul Kwon, Jungwon Park, Philip D. Rack and Ian Papautsky

This work was funded by NSF CBET Award #0729250 and NSF CAREER Award #0640964. A portion of this research was conducted at the Center for Nanophase Materials Sciences, which is sponsored at Oak Ridge National Laboratory by the Division of Scientific User Facilities, U.S. Department of Energy.

Wendy Beckman | EurekAlert!
Further information:
http://www.uc.edu
http://www.uc.edu/news/NR.aspx?id=11597

More articles from Power and Electrical Engineering:

nachricht Nano-scale process may speed arrival of cheaper hi-tech products
09.11.2018 | University of Edinburgh

nachricht Nuclear fusion: wrestling with burning questions on the control of 'burning plasmas'
25.10.2018 | Lehigh University

All articles from Power and Electrical Engineering >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A Chip with Blood Vessels

Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.

Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...

Im Focus: A Leap Into Quantum Technology

Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.

In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...

Im Focus: Research icebreaker Polarstern begins the Antarctic season

What does it look like below the ice shelf of the calved massive iceberg A68?

On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.

Im Focus: Penn engineers develop ultrathin, ultralight 'nanocardboard'

When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure

Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...

Im Focus: Coping with errors in the quantum age

Physicists at ETH Zurich demonstrate how errors that occur during the manipulation of quantum system can be monitored and corrected on the fly

The field of quantum computation has seen tremendous progress in recent years. Bit by bit, quantum devices start to challenge conventional computers, at least...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

“3rd Conference on Laser Polishing – LaP 2018” Attracts International Experts and Users

09.11.2018 | Event News

On the brain’s ability to find the right direction

06.11.2018 | Event News

European Space Talks: Weltraumschrott – eine Gefahr für die Gesellschaft?

23.10.2018 | Event News

 
Latest News

Epoxy compound gets a graphene bump

14.11.2018 | Materials Sciences

Microgel powder fights infection and helps wounds heal

14.11.2018 | Health and Medicine

How algae and carbon fibers could sustainably reduce the athmospheric carbon dioxide concentration

14.11.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>