Scientists at Long Ashton Research Station have identified a gene with a pivotal role in regulating seed germination. According to an article published in the January issue of BBSRC business, the Arabidopsis COMATOSE (CTS) gene, is vital for breaking seed dormancy. It is also analogous to the human X-ALD gene, which featured in the 1992 film "Lorenzos oil". Treatment of cts mutants with a plant version of Lorenzos oil cures their inability to germinate.
The researchers were investigating the genetic control of germination, a key transition in the life of a plant. Once they had cloned the CTS gene, they realised that is analogous to the human adrenoleukodystrophy (ALD) gene, mutation of which results in the build-up of very long chain fatty acids (VLCFAs) and ALD disease. Like human ALD sufferers, cts mutant seeds suffer from a variety of effects including inappropriate accumulation of VLCFAs. They are also unable to germinate. Lorenzo’s oil was developed by Augusto Odone for his son, who is an ALD sufferer, and was recently proven effective for the treatment of pre-symptomatic ALD patients. "We wondered whether Lorenzos oil would work for plants too" says team leader, Dr Mike Holdsworth. Sure enough, when he treated cts mutant seeds with a similar mixture of oils, the seeds became able to germinate.
The Long Ashton researchers believe that CTS protein is important as a fatty acid transporter, but may also have a key role as a regulator of germination. They are continuing to investigate CTS in Arabidopsis, but are also interested in crops such as wheat and oilseed rape, where dormancy levels are associated with quality and performance.
Dr Mike Holdsworth | alfa
Microalgae food for honey bees
12.05.2020 | US Department of Agriculture - Agricultural Research Service
Global trade in soy has major implications for the climate
07.05.2020 | Rheinische Friedrich-Wilhelms-Universität Bonn
In living cells, enzymes drive biochemical metabolic processes enabling reactions to take place efficiently. It is this very ability which allows them to be used as catalysts in biotechnology, for example to create chemical products such as pharmaceutics. Researchers now identified an enzyme that, when illuminated with blue light, becomes catalytically active and initiates a reaction that was previously unknown in enzymatics. The study was published in "Nature Communications".
Enzymes: they are the central drivers for biochemical metabolic processes in every living cell, enabling reactions to take place efficiently. It is this very...
Early detection of tumors is extremely important in treating cancer. A new technique developed by researchers at the University of California, Davis offers a significant advance in using magnetic resonance imaging to pick out even very small tumors from normal tissue. The work is published May 25 in the journal Nature Nanotechnology.
researchers at the University of California, Davis offers a significant advance in using magnetic resonance imaging to pick out even very small tumors from...
Microelectronics as a key technology enables numerous innovations in the field of intelligent medical technology. The Fraunhofer Institute for Biomedical Engineering IBMT coordinates the BMBF cooperative project "I-call" realizing the first electronic system for ultrasound-based, safe and interference-resistant data transmission between implants in the human body.
When microelectronic systems are used for medical applications, they have to meet high requirements in terms of biocompatibility, reliability, energy...
Thomas Heine, Professor of Theoretical Chemistry at TU Dresden, together with his team, first predicted a topological 2D polymer in 2019. Only one year later, an international team led by Italian researchers was able to synthesize these materials and experimentally prove their topological properties. For the renowned journal Nature Materials, this was the occasion to invite Thomas Heine to a News and Views article, which was published this week. Under the title "Making 2D Topological Polymers a reality" Prof. Heine describes how his theory became a reality.
Ultrathin materials are extremely interesting as building blocks for next generation nano electronic devices, as it is much easier to make circuits and other...
Scientists took a leukocyte as the blueprint and developed a microrobot that has the size, shape and moving capabilities of a white blood cell. Simulating a blood vessel in a laboratory setting, they succeeded in magnetically navigating the ball-shaped microroller through this dynamic and dense environment. The drug-delivery vehicle withstood the simulated blood flow, pushing the developments in targeted drug delivery a step further: inside the body, there is no better access route to all tissues and organs than the circulatory system. A robot that could actually travel through this finely woven web would revolutionize the minimally-invasive treatment of illnesses.
A team of scientists from the Max Planck Institute for Intelligent Systems (MPI-IS) in Stuttgart invented a tiny microrobot that resembles a white blood cell...
19.05.2020 | Event News
07.04.2020 | Event News
06.04.2020 | Event News
29.05.2020 | Materials Sciences
29.05.2020 | Materials Sciences
29.05.2020 | Power and Electrical Engineering