Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Genetic test for left-sided displacement of the abomasum (LDA)

23.04.2012
Hannover Veterinary University Scientists sequenced the complete motilin gene in German Holstein cows

Left-sided displacement of the abomasum (LDA) is an economically important disease in Holstein dairy cattle populations all over the world. The bovine abomasum is the equivalent to the stomach in monogastric species and its pathologic displacement is usually preceded by bloating due to reduced gastrointestinal contractions.

Over the past 50 years, the incidence of LDA has considerably increased. Despite surgical veterinary treatments, LDA affected cows show a long convalescence.

Scientists of the Institute for Animal Breeding and Genetics at the University of Veterinary Medicine Hannover Foundation in cooperation with the clinic for cattle of Hannover and the Clinic for Ruminants and Swine, Faculty for Veterinary Medicine at the Justus-Liebig-University Giessen, sequenced the complete motilin gene in German Holstein cows.

They identified a single nucleotide polymorphism showing significant association with LDA and affecting a transcription factor binding site. An expression study gave evidence of a significantly decreased motilin expression in cows carrying the mutant allele. The study indicates motilin to be involved in the etiopathogenesis of LDA in German Holstein cattle.

It provides a first step towards the understanding of the genetics of LDA and may be of use for investigating gastric motility disorders in other species.

You can find further information at the following internet addresses: http://www.tiho-hannover.de/kliniken-institute/institute/institut-fuer-tierzucht-und-vererbungsforschung/gentests/gentests-rind/genombasierter-test-auf-linksseitige-labmagenverlagerung-bei-deutschen-holsteins/
and
http://dx.plos.org/10.1371/journal.pone.0035562

Scientific Contact:

Prof. Dr. Ottmar Distl
Dr. Stefanie Mömke
University of Veterinary Medicine Hannover
Institute for Animal Breeding and Genetics Tel.: +49 511 953-8876
ottmar.distl@tiho-hannover.de
stefanie.moemke@tiho-hannover.de

Sonja von Brethorst | idw
Further information:
http://www.tiho-hannover.de

More articles from Agricultural and Forestry Science:

nachricht Back to Nature: Palm oil plantations are being turned back into protected rainforest
21.03.2019 | Forschungsverbund Berlin e.V.

nachricht The inner struggle of the evening primrose: Chloroplasts are caught up in an evolutionary arms race
14.03.2019 | Max-Planck-Institut für Molekulare Pflanzenphysiologie

All articles from Agricultural and Forestry Science >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: The taming of the light screw

DESY and MPSD scientists create high-order harmonics from solids with controlled polarization states, taking advantage of both crystal symmetry and attosecond electronic dynamics. The newly demonstrated technique might find intriguing applications in petahertz electronics and for spectroscopic studies of novel quantum materials.

The nonlinear process of high-order harmonic generation (HHG) in gases is one of the cornerstones of attosecond science (an attosecond is a billionth of a...

Im Focus: Magnetic micro-boats

Nano- and microtechnology are promising candidates not only for medical applications such as drug delivery but also for the creation of little robots or flexible integrated sensors. Scientists from the Max Planck Institute for Polymer Research (MPI-P) have created magnetic microparticles, with a newly developed method, that could pave the way for building micro-motors or guiding drugs in the human body to a target, like a tumor. The preparation of such structures as well as their remote-control can be regulated using magnetic fields and therefore can find application in an array of domains.

The magnetic properties of a material control how this material responds to the presence of a magnetic field. Iron oxide is the main component of rust but also...

Im Focus: Self-healing coating made of corn starch makes small scratches disappear through heat

Due to the special arrangement of its molecules, a new coating made of corn starch is able to repair small scratches by itself through heat: The cross-linking via ring-shaped molecules makes the material mobile, so that it compensates for the scratches and these disappear again.

Superficial micro-scratches on the car body or on other high-gloss surfaces are harmless, but annoying. Especially in the luxury segment such surfaces are...

Im Focus: Stellar cartography

The Potsdam Echelle Polarimetric and Spectroscopic Instrument (PEPSI) at the Large Binocular Telescope (LBT) in Arizona released its first image of the surface magnetic field of another star. In a paper in the European journal Astronomy & Astrophysics, the PEPSI team presents a Zeeman- Doppler-Image of the surface of the magnetically active star II Pegasi.

A special technique allows astronomers to resolve the surfaces of faraway stars. Those are otherwise only seen as point sources, even in the largest telescopes...

Im Focus: Heading towards a tsunami of light

Researchers at Chalmers University of Technology and the University of Gothenburg, Sweden, have proposed a way to create a completely new source of radiation. Ultra-intense light pulses consist of the motion of a single wave and can be described as a tsunami of light. The strong wave can be used to study interactions between matter and light in a unique way. Their research is now published in the scientific journal Physical Review Letters.

"This source of radiation lets us look at reality through a new angle - it is like twisting a mirror and discovering something completely different," says...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

International Modelica Conference with 330 visitors from 21 countries at OTH Regensburg

11.03.2019 | Event News

Selection Completed: 580 Young Scientists from 88 Countries at the Lindau Nobel Laureate Meeting

01.03.2019 | Event News

LightMAT 2019 – 3rd International Conference on Light Materials – Science and Technology

28.02.2019 | Event News

 
Latest News

Laser processing is a matter for the head – LZH at the Hannover Messe 2019

25.03.2019 | Trade Fair News

A Varied Menu

25.03.2019 | Life Sciences

‘Time Machine’ heralds new era

25.03.2019 | Information Technology

VideoLinks
Science & Research
Overview of more VideoLinks >>>