Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

UAB Oncologists Report HPV Vaccine Also Protects Females From Post-Surgical Cancer Recurrence

17.03.2010
A vaccine designed to prevent cervical cancer also may protect females from post-surgical recurrence of the disease, according to researchers at the University of Alabama at Birmingham (UAB).

A new study shows that the Gardasil vaccine reduces the likelihood of human papillomavirus (HPV)-related disease recurring after teen and adult women already have had surgery to remove cancer or certain pre-cancerous changes, said Warner Huh, M.D., an associate professor in the UAB Division of Gynecologic Oncology and lead presenter on the study.

The findings were announced March 15 at the annual meeting of the Society of Gynecological Oncologists in Chicago.

The study shows that Gardasil reduces by approximately 40 percent the chances that more cancer or pre-cancerous changes will occur in the cervix, vagina and vulva up to 3.8 years after a female has surgery for one of those conditions.

Huh said the findings are important because they answer a question many women and their doctors have been asking - does an HPV vaccine help treat virus-related changes in the body after women have surgery to treat similar changes?

"Based on this study, the data is compelling and suggests it does help to treat virus-related changes," Huh said. "Knowing that Gardasil also may offer postoperative protection from recurrent disease will be crucial in follow-up care and overall health planning for teens and women."

The vaccine is approved to fight the four HPV strains believed to cause 70 percent of cervical cancers and more than 90 percent of genital warts

The study involved 17,622 women ages 15 to 26 from two clinical trials, some who were vaccinated and some who were not. Hundreds of study participants had surgery to remove cancer or certain pre-cancerous changes of the cervix, vagina and vulva and to remove genital warts.

Huh said the results are encouraging because patients treated for HPV-related disease are known to be at higher risk for contracting the same disease post-operatively. Reducing the risk and need of a secondary procedure is an important step in improving women's care, he said.

*Note: Huh maintains a consulting relationship with Gardasil-maker Merck & Co., Inc.

About the UAB Division of Gynecologic Oncology
The UAB Division of Gynecologic Oncology provides comprehensive prevention, detection and cure of female cancers, including cancers of the ovary, uterus, cervix, vagina and vulva, plus treatment of certain benign conditions requiring complicated pelvic surgery. Its physicians are leaders in their fields in a nationally ranked program dedicated to research, leading-edge treatments and community outreach. The division works closely with the UAB Comprehensive Cancer Center and the Lynne Cohen Clinic at UAB, which offers a team approach to cancer risk assessment, treatment and survival care.
Media Contact:
Troy Goodman
(205) 934-8938
tdgoodman@uab.edu

Troy Goodman | EurekAlert!
Further information:
http://www.uab.edu

More articles from Studies and Analyses:

nachricht Study relating to materials testing Detecting damages in non-magnetic steel through magnetism
23.07.2018 | Technische Universität Kaiserslautern

nachricht Innovative genetic tests for children with developmental disorders and epilepsy
11.07.2018 | Christian-Albrechts-Universität zu Kiel

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: New interactive machine learning tool makes car designs more aerodynamic

Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.

When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...

Im Focus: Robots as 'pump attendants': TU Graz develops robot-controlled rapid charging system for e-vehicles

Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.

Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....

Im Focus: The “TRiC” to folding actin

Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.

Actin is the most abundant protein in highly developed cells and has diverse functions in processes like cell stabilization, cell division and muscle...

Im Focus: Lining up surprising behaviors of superconductor with one of the world's strongest magnets

Scientists have discovered that the electrical resistance of a copper-oxide compound depends on the magnetic field in a very unusual way -- a finding that could help direct the search for materials that can perfectly conduct electricity at room temperatur

What happens when really powerful magnets--capable of producing magnetic fields nearly two million times stronger than Earth's--are applied to materials that...

Im Focus: World record: Fastest 3-D tomographic images at BESSY II

The quality of materials often depends on the manufacturing process. In casting and welding, for example, the rate at which melts solidify and the resulting microstructure of the alloy is important. With metallic foams as well, it depends on exactly how the foaming process takes place. To understand these processes fully requires fast sensing capability. The fastest 3D tomographic images to date have now been achieved at the BESSY II X-ray source operated by the Helmholtz-Zentrum Berlin.

Dr. Francisco Garcia-Moreno and his team have designed a turntable that rotates ultra-stably about its axis at a constant rotational speed. This really depends...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Within reach of the Universe

08.08.2018 | Event News

A journey through the history of microscopy – new exhibition opens at the MDC

27.07.2018 | Event News

2018 Work Research Conference

25.07.2018 | Event News

 
Latest News

'Building up' stretchable electronics to be as multipurpose as your smartphone

14.08.2018 | Information Technology

During HIV infection, antibody can block B cells from fighting pathogens

14.08.2018 | Life Sciences

First study on physical properties of giant cancer cells may inform new treatments

14.08.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>