The two year study focused on identifying the key social, organisational and managerial factors that influence clinical research projects in the UK. In the first study of its kind, the researchers carried out a national survey in which they interviewed key stakeholders and surveyed 247 clinical research projects about the challenges of managing clinical research.
The study found that although patient recruitment was and remains a major challenge, retaining the project team was seen as critical to the ongoing success of clinical research and that this was becoming increasingly difficult.
Additionally the research found that retaining the research team throughout the project was significantly hampered by aspects of the approval process; projects which had been approved by the regulatory bodies often then encountered difficulty in obtaining approval from the hospital Trusts and that there was huge variation in both the time and requirements needed to gain approval from these Trusts.
Professor Jacky Swan of Warwick Business School commented, "The problem is that to commercial organisations, time is very important and although many are committed to carrying out clinical research in this country, many are finding it easier to do this research abroad and that does have long term and significant implications for high quality research in the UK and also for the retention of skilled researchers."
Additionally, Professor Swan stressed that the inconsistencies and lengthiness of the approvals processes has a detrimental effect on the completion rates of non- commercial organisations.
"There are three elements of approval; regulation, ethics and research and development and although there has been improvement in regulation and there have been efforts to streamline the R&D process, these are not happening quickly enough to have a positive impact." she added.
"Far more policy attention is needed to address these problems; especially around the skills shortages that are emerging and aspects of the NHS culture which are making it very difficult to conduct the innovative, world-leading clinical research that the UK has always been known for." added Maxine Robertson, Professor of Innovation and Organisation at Queen Mary, University of London.
The majority of the 247 research projects in this study were projects which had been carried out in the last two years. The length of time each took to receive approval included the time for preparation of submissions and not simply the time from submission to approval.A full copy is available on request.
Professor Jacky Swan | EurekAlert!
Innovative genetic tests for children with developmental disorders and epilepsy
11.07.2018 | Christian-Albrechts-Universität zu Kiel
Oxygen loss in the coastal Baltic Sea is “unprecedentedly severe”
05.07.2018 | European Geosciences Union
For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.
To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...
For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.
Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...
Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.
A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...
Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.
"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....
Ultra-short, high-intensity X-ray flashes open the door to the foundations of chemical reactions. Free-electron lasers generate these kinds of pulses, but there is a catch: the pulses vary in duration and energy. An international research team has now presented a solution: Using a ring of 16 detectors and a circularly polarized laser beam, they can determine both factors with attosecond accuracy.
Free-electron lasers (FELs) generate extremely short and intense X-ray flashes. Researchers can use these flashes to resolve structures with diameters on the...
13.07.2018 | Event News
12.07.2018 | Event News
03.07.2018 | Event News
16.07.2018 | Physics and Astronomy
16.07.2018 | Life Sciences
16.07.2018 | Earth Sciences