Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Study finds decreased life expectancy for multiple sclerosis patients

22.01.2014
The first large scale study in the U.S. on the mortality of patients with multiple sclerosis (MS) has been published and provides new information about the life expectancy of people with the disease. The study appears in the journal Multiple Sclerosis and Related Disorders.

David Kaufman, ScD, of the Slone Epidemiology Center at Boston University, is the lead author. The work is the result of a collaboration between the investigators at BU and their colleagues at University of California San Francisco, the University of Alabama, Heinrich Heine University in Düsseldorf, Care-Safe LLC, a consulting firm and the sponsor of the research, Bayer HealthCare Pharmaceuticals.

MS is a chronic disease of the central nervous system which progresses into a degenerative phase in the majority of affected patients. There are 250,000-350,000 patients with MS in the United States, giving an overall prevalence of roughly one in 1,000.

The investigators used health insurance claims data to identify a series of patients with MS and a comparison group of individuals from the same health plans who did not have MS. A total of 30,402 MS patients and 89,818 non-MS subjects who were in the OptumInsight Research (OIR) database from 1996-2009 were included in the study. Data on deaths was obtained from government databases of death records.

Annual mortality rates were 899/100,000 in MS patients and 446/100,000 in comparators. The median lifespan was 6 years less among the MS patients than among the non-MS group. "Our findings are consistent with what has been reported elsewhere in the world," explained Kaufman. "While the results apply only to the commercially insured U.S. population, that group represents more than two-thirds of individuals under age 65, and this is the first time an MS survival disadvantage has been shown in this country."

While early mortality due to MS is relatively rare, the new data confirm that compared to the general population, MS patients in the US do experience a decrease in life expectancy. Most of the information on survival patterns in MS has come from Europe, where populations, risk factors and medical practice may be different than in the U.S.

With the large number of MS patients in the U.S., the lack of data represented a significant knowledge gap. Future studies with longer follow-up periods can provide important information about how the introduction of anti-MS drugs in the 1990s has impacted survival in MS.

Gina DiGravio | EurekAlert!
Further information:
http://www.bmc.org

Further reports about: chronic disease multiple sclerosis risk factor

More articles from Studies and Analyses:

nachricht Innovative genetic tests for children with developmental disorders and epilepsy
11.07.2018 | Christian-Albrechts-Universität zu Kiel

nachricht Oxygen loss in the coastal Baltic Sea is “unprecedentedly severe”
05.07.2018 | European Geosciences Union

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: First evidence on the source of extragalactic particles

For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.

To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...

Im Focus: Magnetic vortices: Two independent magnetic skyrmion phases discovered in a single material

For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.

Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...

Im Focus: Breaking the bond: To take part or not?

Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.

A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...

Im Focus: New 2D Spectroscopy Methods

Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.

"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....

Im Focus: Chemical reactions in the light of ultrashort X-ray pulses from free-electron lasers

Ultra-short, high-intensity X-ray flashes open the door to the foundations of chemical reactions. Free-electron lasers generate these kinds of pulses, but there is a catch: the pulses vary in duration and energy. An international research team has now presented a solution: Using a ring of 16 detectors and a circularly polarized laser beam, they can determine both factors with attosecond accuracy.

Free-electron lasers (FELs) generate extremely short and intense X-ray flashes. Researchers can use these flashes to resolve structures with diameters on the...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Leading experts in Diabetes, Metabolism and Biomedical Engineering discuss Precision Medicine

13.07.2018 | Event News

Conference on Laser Polishing – LaP: Fine Tuning for Surfaces

12.07.2018 | Event News

11th European Wood-based Panel Symposium 2018: Meeting point for the wood-based materials industry

03.07.2018 | Event News

 
Latest News

Global study of world's beaches shows threat to protected areas

19.07.2018 | Earth Sciences

New creepy, crawly search and rescue robot developed at Ben-Gurion U

19.07.2018 | Power and Electrical Engineering

Metal too 'gummy' to cut? Draw on it with a Sharpie or glue stick, science says

19.07.2018 | Materials Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>