Study Offers Piece of “Missing Link” Needed in Understanding Receptor Function—Possibly Providing Safe, Ethical Source for Replacing Brain Cells, Reports March Journal of Nuclear Medicine
Japanese researchers have found a piece of the “missing link” about how bone marrow stromal cells restore lost neurologic function when transplanted into animals exhibiting central nervous system disorders, according to a study in the March issue of the Journal of Nuclear Medicine.
“Our study showed that cell transplantation therapy may improve brain receptor function in patients who suffered from cerebral stroke, improving their neurological symptoms,” said Satoshi Kuroda, M.D., Ph.D., who is with the department of neurosurgery at Hokkaido University School of Medicine in Sapporo, Japan. “How the transplanted bone marrow stromal cells restore the lost neurologic function is not clear,” added the co-author of “Improved Expression of ã-Aminobutyric Acid Receptor in Mice With Cerebral Infarct and Transplanted Bone Marrow Stromal Cells: An Autoradiographic and Histologic Analysis.”
Maryann Verrillo | EurekAlert!
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