Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New study shows women more vulnerable to risk of colorectal cancer from tobacco

31.10.2005


Another study demonstrates benefits of colon cancer screening in elderly populations



A new study of gender and risk factors for colorectal cancer reveals that while both tobacco and alcohol increase risk for colorectal cancer, women who smoke are at higher risk. Researcher Anna L. Zisman, M.D. of Evanston Northwestern Health Care presented these findings at the 70th Annual Scientific Meeting of the American College of Gastroenterology. Another study presented at ACG of patients undergoing colonoscopy demonstrated that patients over 75 benefit from colorectal cancer screening in detecting cancer and potentially cancerous lesions and experience no more complications from colonoscopy than younger patients.

Smoking Significantly Increases Colorectal Cancer Risk in Women


Smoking and alcohol use are well-established risk factors for colorectal cancer. According to Dr. Zisman, "Understanding interactions between genetic and environmental factors, such as smoking and alcohol use, is critical for colorectal cancer risk stratification, and will help us design effective screening strategies."

Dr. Zisman and her colleagues looked at women’s susceptibility compared to men. Using the IMPAC Medical Registry Services Cancer Information Resource File, a large database from over 350 teaching and community hospitals, the investigators conducted a regression analysis of gender, tobacco and alcohol use. They found that while age of onset of colorectal cancer was slightly younger in males than females in the non-smoking/non-drinking group, current smokers had a markedly decreased age of presentation for both men and women. Similarly, alcohol use was associated with an earlier age of diagnosis in males and females. An assessment of the differential sensitivity to smoking and alcohol use in men and women revealed that women are sensitive to smoking as a risk factor for colorectal cancer but not alcohol. "We can see that while both men and women who use tobacco and alcohol are diagnosed with colorectal cancer at an earlier age, the effect of tobacco is significantly greater in women," said Dr. Zisman.

Colorectal Cancer Screening Benefits Patients 75 Years and Older

Most guidelines recommend that screening for colorectal cancer should begin at age 50 for individuals at average risk. "However there is no consensus regarding the age at which we should stop screening," commented Aaron Walfish, M.D. of Beth Israel Medical Center in New York. According to Dr. Walfish, "Older patients often have other health problems that increase the risk of undergoing endoscopy, so we need more evidence regarding the usefulness of screening in this older population. Our data support continued screening of elderly patients."

Dr. Walfish and his colleagues conducted a retrospective analysis of 178 patients 75 and older and 318 patients between ages 65 and 69. In both age groups, the researchers found that a similar percentage of patients had polyps or masses (43 percent in the 75 and older group vs. 42 percent in the 65 to 69 group), and that a similar percentage had larger polyps or masses (49 percent in the 75 and older group vs. 58 percent in the 65 to 69 group had polyps greater than or equal to 1 cm.) There were no complications from the screening procedure reported in either age group.

Anne-Louise Oliphant | EurekAlert!
Further information:
http://www.acg.gi.org
http://www.ibsrelief.org

More articles from Studies and Analyses:

nachricht Innovative genetic tests for children with developmental disorders and epilepsy
11.07.2018 | Christian-Albrechts-Universität zu Kiel

nachricht Oxygen loss in the coastal Baltic Sea is “unprecedentedly severe”
05.07.2018 | European Geosciences Union

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Future electronic components to be printed like newspapers

A new manufacturing technique uses a process similar to newspaper printing to form smoother and more flexible metals for making ultrafast electronic devices.

The low-cost process, developed by Purdue University researchers, combines tools already used in industry for manufacturing metals on a large scale, but uses...

Im Focus: First evidence on the source of extragalactic particles

For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.

To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...

Im Focus: Magnetic vortices: Two independent magnetic skyrmion phases discovered in a single material

For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.

Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...

Im Focus: Breaking the bond: To take part or not?

Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.

A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...

Im Focus: New 2D Spectroscopy Methods

Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.

"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Leading experts in Diabetes, Metabolism and Biomedical Engineering discuss Precision Medicine

13.07.2018 | Event News

Conference on Laser Polishing – LaP: Fine Tuning for Surfaces

12.07.2018 | Event News

11th European Wood-based Panel Symposium 2018: Meeting point for the wood-based materials industry

03.07.2018 | Event News

 
Latest News

A smart safe rechargeable zinc ion battery based on sol-gel transition electrolytes

20.07.2018 | Power and Electrical Engineering

Reversing cause and effect is no trouble for quantum computers

20.07.2018 | Information Technology

Princeton-UPenn research team finds physics treasure hidden in a wallpaper pattern

20.07.2018 | Materials Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>