Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

’Good’ bacteria helps ease pain of colitis

26.07.2005


A mixture of bacteria developed in part by University of Alberta researchers has been proven highly effective in treating people suffering from ulcerative colitis.

The findings, published in the July, 2005 issue of American Journal of Gastroenterology showed that the majority of patients taking a probiotic mixture of 8 bacteria (VSL#3) for 6 weeks improved their ulcerative colitis. Probiotics are preparations of living microbial cells that, when ingested, are thought to positively influence the composition of microbes in the gut and improve the health of the intestine.

While "bad" bacteria have been flagged as potential culprits in the cause of inflammatory diseases of the bowel, in this case, the ingestion of supplemental "good" bacteria (probiotics) to the intestine proved beneficial in treating ulcerative colitis, said Dr. Richard Fedorak, a professor of gastroenterology at the University of Alberta. The joint study included researchers from the University of Bologna in Italy and the University of North Carolina.



In this open label clinical trial, 86 per cent of those treated with probiotic bacteria mixture VSL#3 experienced relief of their mild to moderate ulcerative colitis. The mixture of eight lactic acid bacterial species is believed to be effective by mechanisms that include (1) reducing the number of "bad" bacteria, (2) reducing the amount of inflammation (3) increasing the mucus layer in the gut, and (4) increasing the amount of anti-inflammatory molecules in the intestine.

Ulcerative colitis is an inflammatory bowel disease that affects the large intestine (colon) and causes acute bloody diarrhea, sever stomach pain, urgency, anemia and fatigue. In its most severe form, ulcerative colitis that does not respond to medical treatment will require surgical removal of the colon.

The VSL#3 was administered over a six-week period to 30 patients who ranged in age from 18 to 65. Remission of the colitis was achieved in 63 per cent of the patients, while another 23 per cent responded with improvement in their symptoms and with healing of the colon’s lining. There were no adverse effects to the medication.

The VSL#3 can be considered an important potential treatment for those patients who don’t respond to conventional therapy such as mesalamine or 5ASA, Dr. Fedorak said.

Bev Betkowski | EurekAlert!
Further information:
http://www.ualberta.ca

More articles from Studies and Analyses:

nachricht Innovative genetic tests for children with developmental disorders and epilepsy
11.07.2018 | Christian-Albrechts-Universität zu Kiel

nachricht Oxygen loss in the coastal Baltic Sea is “unprecedentedly severe”
05.07.2018 | European Geosciences Union

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: First evidence on the source of extragalactic particles

For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.

To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...

Im Focus: Magnetic vortices: Two independent magnetic skyrmion phases discovered in a single material

For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.

Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...

Im Focus: Breaking the bond: To take part or not?

Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.

A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...

Im Focus: New 2D Spectroscopy Methods

Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.

"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....

Im Focus: Chemical reactions in the light of ultrashort X-ray pulses from free-electron lasers

Ultra-short, high-intensity X-ray flashes open the door to the foundations of chemical reactions. Free-electron lasers generate these kinds of pulses, but there is a catch: the pulses vary in duration and energy. An international research team has now presented a solution: Using a ring of 16 detectors and a circularly polarized laser beam, they can determine both factors with attosecond accuracy.

Free-electron lasers (FELs) generate extremely short and intense X-ray flashes. Researchers can use these flashes to resolve structures with diameters on the...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Leading experts in Diabetes, Metabolism and Biomedical Engineering discuss Precision Medicine

13.07.2018 | Event News

Conference on Laser Polishing – LaP: Fine Tuning for Surfaces

12.07.2018 | Event News

11th European Wood-based Panel Symposium 2018: Meeting point for the wood-based materials industry

03.07.2018 | Event News

 
Latest News

Machine-learning predicted a superhard and high-energy-density tungsten nitride

18.07.2018 | Materials Sciences

NYSCF researchers develop novel bioengineering technique for personalized bone grafts

18.07.2018 | Life Sciences

Why might reading make myopic?

18.07.2018 | Health and Medicine

VideoLinks
Science & Research
Overview of more VideoLinks >>>