Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Early detection of lung cancer

20.04.2005


This study was aimed at the detection of lung cancer in its early stages amongst high-risk persons by means of Computerised Axial Tomography (CAT).



Currently, 85% of cases are diagnosed at a late stage, which considerably reduces the rate of cure.

Lung cancer is the most common carcinoma in western countries and the one that causes most deaths; more than those caused by breast cancer, cancer of the colon and prostate cancer put together.


Tobacco is the main cause of this illness, with the risk of it arising persisting even twenty years after giving up smoking. In general this pathology is diagnosed on its symptoms appearing, indicating that it is at an advanced stage and with poor prognosis. In fact, using traditional techniques, only 15% of cases are detected at an early stage; this is why it is essential to find tools for early detection which will guarantee the curing of the illness.

The research by the Lung Service at the Navarre University Hospital used thoracic CAT to periodically analyse persons at high risk of developing lung cancer, i.e. over-forties who have smoked at least one packet a day over ten years. The study is part of the ELCAP (Early Lung Cancer Action Program), international project in which centres from the United States, Europe, Japan, China and Israel participated.

Results

The research proved the efficacy of this imaging technique for the early-stage detection of lung cancer. The published results correspond to the first 1000 persons who took part in the project at the University Hospital. Concretely, cancer was detected in 14 individuals, thirteen at stage 1, the earliest and most curable stage. This work confirmed the conclusions obtained by ELCAP from more than 30,000 persons.

Despite the direct link between tobacco and lung cancer, only 15% of smokers develop the disease. Thus, it is fundamental to find any risk factors that predispose having this pathology. This study discovered that there was a greater risk amongst asymptomatic smokers than amongst those who were diagnosed with obstructive pulmonary disease with spirometry. In any case, it is essential to continue with these lines of research aimed at identifying the population at high risk with precision. Specifically, a priority line of investigation at the University Hospital and the CIMA Centre at Navarre University involves the study of biomolecular techniques and their combination with radiological tests that help in the early detection of lung cancer.

Once the first results are published, the project will continue to review, by means of CAT, those patients who have not developed the illness. What is wanted is a better definition of the use of this technique in order to judge its efficacy in the detection of new cancers amongst this population at risk. Moreover, the effect of this monitoring on the weaning of participants off the tobacco habit will be analysed.

Irati Kortabitarte | EurekAlert!
Further information:
http://www.basqueresearch.com/
http://www.elhuyar.com
http://www.unav.es/cun

More articles from Studies and Analyses:

nachricht Study relating to materials testing Detecting damages in non-magnetic steel through magnetism
23.07.2018 | Technische Universität Kaiserslautern

nachricht Innovative genetic tests for children with developmental disorders and epilepsy
11.07.2018 | Christian-Albrechts-Universität zu Kiel

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Unraveling the nature of 'whistlers' from space in the lab

A new study sheds light on how ultralow frequency radio waves and plasmas interact

Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...

Im Focus: New interactive machine learning tool makes car designs more aerodynamic

Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.

When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...

Im Focus: Robots as 'pump attendants': TU Graz develops robot-controlled rapid charging system for e-vehicles

Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.

Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....

Im Focus: The “TRiC” to folding actin

Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.

Actin is the most abundant protein in highly developed cells and has diverse functions in processes like cell stabilization, cell division and muscle...

Im Focus: Lining up surprising behaviors of superconductor with one of the world's strongest magnets

Scientists have discovered that the electrical resistance of a copper-oxide compound depends on the magnetic field in a very unusual way -- a finding that could help direct the search for materials that can perfectly conduct electricity at room temperatur

What happens when really powerful magnets--capable of producing magnetic fields nearly two million times stronger than Earth's--are applied to materials that...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Within reach of the Universe

08.08.2018 | Event News

A journey through the history of microscopy – new exhibition opens at the MDC

27.07.2018 | Event News

2018 Work Research Conference

25.07.2018 | Event News

 
Latest News

Unraveling the nature of 'whistlers' from space in the lab

15.08.2018 | Physics and Astronomy

Diving robots find Antarctic winter seas exhale surprising amounts of carbon dioxide

15.08.2018 | Earth Sciences

Early opaque universe linked to galaxy scarcity

15.08.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>