Administering hormonal treatment in addition to radiation therapy in patients with high-risk prostate cancer can improve survival rate, according to a new study published in the April 1, 2005, issue of the International Journal of Radiation Oncology*Biology*Physics, the official journal of ASTRO, the American Society for Therapeutic Radiology and Oncology.
The study, conducted between1987 and 1992, separated 977 patients into two groups: the adjuvant arm and the observation arm. Those in the adjuvant arm received radiation therapy and goserelin acetatc, a type of hormonal agent. The patients in the observation arm received radiation therapy only. Goserelin acetatc was administered only if they experienced a relapse.
As of July 2003, the median follow-up for all patients was 7.6 years and for surviving patients, 11 years. At ten years, the overall survival rate was significantly higher for the adjuvant arm than the observation arm – 49 percent to 39 percent, respectively. The local failure rate at ten years for the adjuvant arm was 23 percent and 38 percent for the observation arm and the ten year rates for cancer metastasizing to other parts of the body were 24 percent for the adjuvant patients versus 399 percent for the observation patients. Finally, the prostate cancer-related death rate was 16 percent for adjuvant and 22 percent for the observation arm.
Nick Lashinsky | EurekAlert!
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There are currently great hopes for solid-state batteries. They contain no liquid parts that could leak or catch fire. For this reason, they do not require cooling and are considered to be much safer, more reliable, and longer lasting than traditional lithium-ion batteries. Jülich scientists have now introduced a new concept that allows currents up to ten times greater during charging and discharging than previously described in the literature. The improvement was achieved by a “clever” choice of materials with a focus on consistently good compatibility. All components were made from phosphate compounds, which are well matched both chemically and mechanically.
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