Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Multi-Center Study Shows Link Between Residential Radon And Lung Cancer

15.03.2005


Two University of Iowa researchers were part of a large multi-center study that provides compelling direct evidence of an association between prolonged residential radon exposure and lung cancer risk.



The study, an analysis of data pooled from seven different North American residential radon studies, demonstrates an 11 to 21 percent increased lung cancer risk at average residential radon concentrations of approximately 3.0 picocuries per liter of air, during an exposure period of 5 to 30 years. The lung cancer risk increased with increasing radon exposure. The U.S. Environmental Protection Agency’s current action level for residential radon is 4.0 picocuries per liter.

"This analysis, based on the largest radon data set assembled in North America, agrees with a similar large-scale radon pooled analysis performed concurrently in Europe. The North American and European pooling provides unambiguous and direct evidence of an increased lung cancer risk even at residential radon exposure levels below the U.S. EPA’s action level," according to R. William Field, Ph.D., UI associate professor of occupational and environmental health and epidemiology, and a co-author of the study, which is reported in the March 2005 issue of the journal Epidemiology. Charles F. Lynch, M.D., Ph.D., professor of epidemiology, also contributed to the research.


Radon is the second-leading cause of lung cancer in the United States with an estimated 21,000 lung cancer deaths each year related to radon exposure, according to EPA. A radioactive, invisible, odorless gas that comes from the decay of naturally occurring uranium in the earth’s soil, radon can accumulate in enclosed areas, such as underground mines and homes.

The initial link between radon exposure and lung cancer had been derived from studies of underground miners, who are exposed at much higher levels to the radioactive gas, and from animal and in vitro studies. Some previous case-control studies reported a positive or weakly positive association between lung cancer risk and residential radon concentrations, while others found no evidence of an association. The North American pooling study was designed to assess the seemingly disparate findings from these earlier studies.

Field and Lynch were part of an international team of researchers who performed the combined analysis of the original residential radon studies, conducted in Connecticut, Iowa, New Jersey, Missouri, and Utah and South Idaho, as well as Winnipeg, Canada. The original studies were funded from several federal sources, including the National Institute of Environmental Health Sciences and the National Cancer Institute. The investigators’ review of 3,662 cases and 4,966 controls from these combined studies represents the largest analytic radon epidemiologic study ever performed in North America.

"The findings from the previously performed Iowa Residential Radon Lung Cancer Study indicate the risk estimates from this pooled analyses actually may slightly underestimate the true risk posed by prolonged residential radon exposure," Field said, noting potential exposure misclassification resulting from the pooling techniques. Investigators are currently pooling the results from the North American and European studies.

Simple, inexpensive do-it-yourself radon test kits are available at local hardware stores. EPA recommends that houses with radon levels of 4 picocuries per liter or higher of radon should and can be fixed to prevent accumulation of radon gas indoors. To learn more about how to receive a discounted radon home test kit, for more information about radon and to contact your state radon office, visit: http://www.epa.gov/radon/ or call 1-800-SOS-RADON.

STORY SOURCE: College of Public Health Office of Communications, 4261 Westlawn, Iowa City, IA, 52242.

Dan McMillan | EurekAlert!
Further information:
http://www.uiowa.edu

More articles from Studies and Analyses:

nachricht Study relating to materials testing Detecting damages in non-magnetic steel through magnetism
23.07.2018 | Technische Universität Kaiserslautern

nachricht Innovative genetic tests for children with developmental disorders and epilepsy
11.07.2018 | Christian-Albrechts-Universität zu Kiel

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Color effects from transparent 3D-printed nanostructures

New design tool automatically creates nanostructure 3D-print templates for user-given colors
Scientists present work at prestigious SIGGRAPH conference

Most of the objects we see are colored by pigments, but using pigments has disadvantages: such colors can fade, industrial pigments are often toxic, and...

Im Focus: Unraveling the nature of 'whistlers' from space in the lab

A new study sheds light on how ultralow frequency radio waves and plasmas interact

Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...

Im Focus: New interactive machine learning tool makes car designs more aerodynamic

Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.

When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...

Im Focus: Robots as 'pump attendants': TU Graz develops robot-controlled rapid charging system for e-vehicles

Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.

Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....

Im Focus: The “TRiC” to folding actin

Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.

Actin is the most abundant protein in highly developed cells and has diverse functions in processes like cell stabilization, cell division and muscle...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

LaserForum 2018 deals with 3D production of components

17.08.2018 | Event News

Within reach of the Universe

08.08.2018 | Event News

A journey through the history of microscopy – new exhibition opens at the MDC

27.07.2018 | Event News

 
Latest News

Smallest transistor worldwide switches current with a single atom in solid electrolyte

17.08.2018 | Physics and Astronomy

Robots as Tools and Partners in Rehabilitation

17.08.2018 | Information Technology

Climate Impact Research in Hannover: Small Plants against Large Waves

17.08.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>