A newly designed endoscope, capable of providing sub-second polarized spectral images of tissue in vivo (in the body), allows physicians and surgeons to non-invasively survey and sample an entire area without actually removing tissue, and may offer hope as a new tool for detecting cancer early. Researchers from Cedars-Sinai Medical Center in Los Angeles and Carnegie Mellon University in Pittsburgh describe the instrument’s capabilities and clinical applications in the July 2004 issue of Progress in Biomedical Optics and Imaging.
The new device, named the Hyperspectral Imaging Endoscope (HSIE), is a standard medical endoscope enhanced with a customized imaging fiber. Working together with a camera, a laptop computer and a tunable light source covering the visible and near-infrared range, the HSIE system is capable of acquiring rapid spectral images of tissues, allowing physicians to non-invasively survey and sample an entire area of tissue in vivo (within the body). Compared to traditional biopsy where a small amount of tissue is removed and then examined in a laboratory, the HSIE system provides a non-contact method of gaining as much information as possible about an area without removing any tissue.
The system is relatively simple and based on the intrinsic properties of tissue and light, explains Daniel Farkas, Ph.D., Director of the Minimally Invasive Surgical Technologies Institute at Cedars-Sinai, and one of the study authors. “When light impacts tissue, it gives back a certain scattering pattern with spectral oscillations depending on the size of the scattering object. This pattern gives us a relatively quantitative idea whether or not a tissue area contains cancerous cells since the nuclei of cells in pre-cancerous and cancerous tissues are enlarged. The theory and spectroscopy have been beautifully worked out by our colleagues in Boston and Los Alamos, and we have now moved this type of investigation into the endoscopic imaging domain.”
Sandra Van | Cedars-Sinai Media
Study relating to materials testing Detecting damages in non-magnetic steel through magnetism
23.07.2018 | Technische Universität Kaiserslautern
Innovative genetic tests for children with developmental disorders and epilepsy
11.07.2018 | Christian-Albrechts-Universität zu Kiel
Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...
Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.
When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...
Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.
Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....
Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.
Actin is the most abundant protein in highly developed cells and has diverse functions in processes like cell stabilization, cell division and muscle...
Scientists have discovered that the electrical resistance of a copper-oxide compound depends on the magnetic field in a very unusual way -- a finding that could help direct the search for materials that can perfectly conduct electricity at room temperatur
What happens when really powerful magnets--capable of producing magnetic fields nearly two million times stronger than Earth's--are applied to materials that...
08.08.2018 | Event News
27.07.2018 | Event News
25.07.2018 | Event News
16.08.2018 | Life Sciences
16.08.2018 | Earth Sciences
16.08.2018 | Life Sciences