Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

$100,000 Grant Funds Further Study of Retinal Cell Transplantation

16.07.2004


The University of Utah’s John A. Moran Eye Center has received a $100,000 grant from the Stephen A. and Elaine Wynn Charitable Foundation to fund continued research into retinal cell transplantation. The research is expected to help set the stage for human clinical trials of treatments for a blinding eye disease known as Retinitis Pigmentosa (RP).



The funding will support the work of Raymond D. Lund, Ph.D., the Calvin S. and Janeal N. Hatch Presidential Endowed Chair and Professor of Ophthalmology and Visual Sciences at the University of Utah. Groundbreaking research published by Lund’s group in 2002 demonstrated that vision could be preserved in rats born with vision loss similar to the human disease Retinitis Pigmentosa by transplanting healthy cells from human biopsies into their eyes.

“Our initial research showed, in essence, that rats who would have been blind without a transplant were able to discriminate patterns as well as rats with normal vision. Our idea to transplant new cells into the eye to sustain and nurture defective cells is a novel approach that has proven successful beyond expectations,” said Lund.


Before attempting this type of research in humans, however, Lund says there are more questions that need to be answered. Specifically, new research funded by the Wynn Foundation will evaluate whether any safety issues emerge, how late in the animal’s life transplantation can be effective, and how to translate the laboratory experience to the clinic.

“Once we’re satisfied that all of our questions are answered we’ll begin planning for limited human clinical trials,” said Lund. He emphasizes that the trials will include a very small number of RP patients.

According to the Foundation Fighting Blindness (www.blindness.org), patients with RP often experience a ring of vision loss in their mid-periphery with small islands of vision in their very far periphery. Other patients report the sensation of tunnel vision, as though they see the world through a straw. Many RP patients retain a small degree of central vision throughout their life.

Since the opening of the John A. Moran Eye Center in 1993, the Stephen A. and Elaine Wynn Charitable Foundation has provided the center with nearly $500,000 in funding through grants. The Wynn family has also played an important role in fundraising for the center and Mr. Wynn sits on the center’s Advisory Board.

“The goal of the foundation is to provide seed money to scientists and programs whose research is nearing human clinical trials. We’ve been especially impressed with Dr. Lund and his team of scientists because of the great sensitivity they’ve shown to patients suffering from blinding eye diseases. Dr. Lund recognizes that for patients and their families this type of research is a race toward treatment,” according to Steven Dezii, a foundation trustee and spokesperson.

| newswise
Further information:
http://www.hsc.utah.edu

More articles from Studies and Analyses:

nachricht Innovative genetic tests for children with developmental disorders and epilepsy
11.07.2018 | Christian-Albrechts-Universität zu Kiel

nachricht Oxygen loss in the coastal Baltic Sea is “unprecedentedly severe”
05.07.2018 | European Geosciences Union

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Future electronic components to be printed like newspapers

A new manufacturing technique uses a process similar to newspaper printing to form smoother and more flexible metals for making ultrafast electronic devices.

The low-cost process, developed by Purdue University researchers, combines tools already used in industry for manufacturing metals on a large scale, but uses...

Im Focus: First evidence on the source of extragalactic particles

For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.

To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...

Im Focus: Magnetic vortices: Two independent magnetic skyrmion phases discovered in a single material

For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.

Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...

Im Focus: Breaking the bond: To take part or not?

Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.

A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...

Im Focus: New 2D Spectroscopy Methods

Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.

"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Leading experts in Diabetes, Metabolism and Biomedical Engineering discuss Precision Medicine

13.07.2018 | Event News

Conference on Laser Polishing – LaP: Fine Tuning for Surfaces

12.07.2018 | Event News

11th European Wood-based Panel Symposium 2018: Meeting point for the wood-based materials industry

03.07.2018 | Event News

 
Latest News

A smart safe rechargeable zinc ion battery based on sol-gel transition electrolytes

20.07.2018 | Power and Electrical Engineering

Reversing cause and effect is no trouble for quantum computers

20.07.2018 | Information Technology

Princeton-UPenn research team finds physics treasure hidden in a wallpaper pattern

20.07.2018 | Materials Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>