Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Study identifies promising treatment for kidney cancers

01.07.2004


A study of patients with kidney cancer has shown that radiofrequency ablation, a minimally invasive, kidney-sparing procedure, can be a successful treatment option for patients whose cancer has not spread beyond the kidney, report researchers at Wake Forest Baptist Medical Center.



Results from the three year study, which evaluated 22 patients who received the treatment, are published in the July issue of the American Journal of Roentgenology. The treatment uses computed tomography to guide the placement of a special needle-shaped electrode into the tumor. A radiofrequency current is then passed through the electrode to heat the tumor tissue and ablate – or eliminate – it.

Complete tumor ablation was achieved after a single treatment in 83 percent of the patients; an additional eight percent had complete tumor ablation after two or more treatments. None of the patients had long-term or serious complications. "These results are significant and encouraging because the incidence of kidney cancer in the United States has increased by 126 percent over the past 50 years," said Ronald J. Zagoria, professor of radiologic sciences at Wake Forest Baptist and principal investigator of the study.


For the past 50 years, the standard of care for kidney cancer has been radical nephrectomy – removal of the kidney. More recently, partial nephrectomy has been shown to have equivalent results for curing small low-stage renal cancers, indicating that kidney-sparing procedures can be curative. However, nephrectomy is not ideal for many patients, such as those who cannot tolerate surgery because of other health-related conditions.

Advances in imaging techniques have resulted in detecting the tumors when they are much smaller, often in patients who show no symptoms. The success of radiofrequency ablation in treating kidney cancer is largely dependent on tumor size.

In this study, tumors smaller than 3 cm in diameter were completely ablated with a single treatment. Residual tumor was found only in patients with tumors greater than 3.1 cm, suggesting that larger tumors are more difficult to eradicate completely with radiofrequency ablation.

"Radiofrequency ablation offers us another potentially curative option for appropriate patients," said Zagoria. While additional studies are needed to determine its long-term success, it could prove to be a useful treatment for patients who are not ideal surgical candidates. In addition, the length of hospital stay, cost and risk of complications for radiofrequency ablation are projected to be less than for nephrectomy.

Jonnie Rohrer | EurekAlert!
Further information:
http://www.wfubmc.edu

More articles from Studies and Analyses:

nachricht Study relating to materials testing Detecting damages in non-magnetic steel through magnetism
23.07.2018 | Technische Universität Kaiserslautern

nachricht Innovative genetic tests for children with developmental disorders and epilepsy
11.07.2018 | Christian-Albrechts-Universität zu Kiel

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Unraveling the nature of 'whistlers' from space in the lab

A new study sheds light on how ultralow frequency radio waves and plasmas interact

Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...

Im Focus: New interactive machine learning tool makes car designs more aerodynamic

Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.

When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...

Im Focus: Robots as 'pump attendants': TU Graz develops robot-controlled rapid charging system for e-vehicles

Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.

Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....

Im Focus: The “TRiC” to folding actin

Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.

Actin is the most abundant protein in highly developed cells and has diverse functions in processes like cell stabilization, cell division and muscle...

Im Focus: Lining up surprising behaviors of superconductor with one of the world's strongest magnets

Scientists have discovered that the electrical resistance of a copper-oxide compound depends on the magnetic field in a very unusual way -- a finding that could help direct the search for materials that can perfectly conduct electricity at room temperatur

What happens when really powerful magnets--capable of producing magnetic fields nearly two million times stronger than Earth's--are applied to materials that...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Within reach of the Universe

08.08.2018 | Event News

A journey through the history of microscopy – new exhibition opens at the MDC

27.07.2018 | Event News

2018 Work Research Conference

25.07.2018 | Event News

 
Latest News

Staying in Shape

16.08.2018 | Life Sciences

Diving robots find Antarctic seas exhale surprising amounts of carbon dioxide in winter

16.08.2018 | Earth Sciences

Protein droplets keep neurons at the ready and immune system in balance

16.08.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>