Although women normally have androgens – so-called "male" hormones – circulating in their bloodstreams, excessive levels can cause a variety of symptoms including acne, weight gain, excessive hair growth (hirsutism), menstrual dysfunction, and infertility.
Hirsutism – the growth of coarse hair in patterns similar to those of men – has long been considered the key marker for androgen excess. Physicians have had difficulty providing a firm diagnosis and identifying underlying causes, however, because a number of disorders can cause hirsutism, not all women with hirsutism have evidence of androgen excess, and not all patients who have androgen excess disorders suffer from hirsutism. Determining the most effective treatment has been challenging, too. While most women have been treated with single-agent hormone therapy, a combination approach has been suggested as a better alternative, but comparison studies have been conducted in only small samples of patients.
Now a long-term study – perhaps the largest of its kind to date – identifies the most common causes of androgen excess in women and compares therapeutic approaches, showing that combination hormonal therapy can improve most symptoms. Researchers at Cedars-Sinai Medical Center and the University of Alabama at Birmingham report their findings in the February issue of the Journal of Clinical Endocrinology and Metabolism in an "Extensive Personal Experience" article.
Sandra Van | Van Communications
Study relating to materials testing Detecting damages in non-magnetic steel through magnetism
23.07.2018 | Technische Universität Kaiserslautern
Innovative genetic tests for children with developmental disorders and epilepsy
11.07.2018 | Christian-Albrechts-Universität zu Kiel
There are currently great hopes for solid-state batteries. They contain no liquid parts that could leak or catch fire. For this reason, they do not require cooling and are considered to be much safer, more reliable, and longer lasting than traditional lithium-ion batteries. Jülich scientists have now introduced a new concept that allows currents up to ten times greater during charging and discharging than previously described in the literature. The improvement was achieved by a “clever” choice of materials with a focus on consistently good compatibility. All components were made from phosphate compounds, which are well matched both chemically and mechanically.
The low current is considered one of the biggest hurdles in the development of solid-state batteries. It is the reason why the batteries take a relatively long...
New design tool automatically creates nanostructure 3D-print templates for user-given colors
Scientists present work at prestigious SIGGRAPH conference
Most of the objects we see are colored by pigments, but using pigments has disadvantages: such colors can fade, industrial pigments are often toxic, and...
Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...
Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.
When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...
Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.
Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....
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