People with heart failure and normal cholesterol may benefit from cholesterol-lowering drugs called statins, researchers report in todays rapid access issue of Circulation: Journal of the American Heart Association.
"This is the first prospective study to show that statins have beneficial effects in heart failure in the absence of coronary artery disease or high blood cholesterol," says senior author James K. Liao, M.D., director of vascular medicine research at Brigham & Womens Hospital and associate professor of medicine at Harvard Medical School, Boston, Mass. "This was a surprising finding in that the benefits occur after only 14 weeks of treatment and with a very low dose of the drug."
Statins have already been shown to decrease the incidence of chronic heart failure in patients with coronary artery disease and high cholesterol. However, the effect of statins on heart failure in people without cholesterol-induced coronary artery disease is not known.
Carole Bullock | EurekAlert!
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