Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Study suggests chemotherapy diminishes fertility in breast cancer patients

02.06.2008
Pre-menopausal breast cancer survivors who were treated with chemotherapy following surgery were more likely to have diminished ovarian reserve - the capacity of the ovaries to provide eggs capable of being fertilized - compared to women who have never had breast cancer, according to a study led by Dana-Farber Cancer Institute investigators. Their findings will be presented at the annual meeting of the American Society of Clinical Oncology (ASCO), May 30-June 3, in Chicago.

The researchers analyzed markers of ovarian reserve in 20 premenopausal breast cancer patients who had been treated with adjuvant chemotherapy, who were one or more years out from their diagnosis, and who had no evidence of recurrence. This group was compared with a "control" group of 20 like-aged women without a history of the disease.

The evaluation involved five tests conducted two, three or four days after a menstrual cycle to assess the ovaries' physical condition, hormone levels and a compound involved in the menstrual cycle. In four of the five tests, the breast cancer survivors had a worse ovarian reserve than did the control group. The other test showed no major difference between the two groups.

"These findings may have important implications for women who are interested in having children after receiving chemotherapy," said Ann Partridge, MD, MPH, of Dana-Farber, who led the study. "Studies that track breast cancer survivors following treatment are needed to determine the predictive value of these tests for pregnancy."

Bill Schaller | EurekAlert!
Further information:
http://www.dfci.harvard.edu
http://www.dana-farber.org

More articles from Studies and Analyses:

nachricht Forest Bird Community is endangered in South America
12.02.2019 | Humboldt-Universität zu Berlin

nachricht Even psychological placebos have an effect
05.02.2019 | Universität Basel

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Regensburg physicists watch electron transfer in a single molecule

For the first time, an international team of scientists based in Regensburg, Germany, has recorded the orbitals of single molecules in different charge states in a novel type of microscopy. The research findings are published under the title “Mapping orbital changes upon electron transfer with tunneling microscopy on insulators” in the prestigious journal “Nature”.

The building blocks of matter surrounding us are atoms and molecules. The properties of that matter, however, are often not set by these building blocks...

Im Focus: University of Konstanz gains new insights into the recent development of the human immune system

Scientists at the University of Konstanz identify fierce competition between the human immune system and bacterial pathogens

Cell biologists from the University of Konstanz shed light on a recent evolutionary process in the human immune system and publish their findings in the...

Im Focus: Transformation through Light

Laser physicists have taken snapshots of carbon molecules C₆₀ showing how they transform in intense infrared light

When carbon molecules C₆₀ are exposed to an intense infrared light, they change their ball-like structure to a more elongated version. This has now been...

Im Focus: Famous “sandpile model” shown to move like a traveling sand dune

Researchers at IST Austria find new property of important physical model. Results published in PNAS

The so-called Abelian sandpile model has been studied by scientists for more than 30 years to better understand a physical phenomenon called self-organized...

Im Focus: Cryo-force spectroscopy reveals the mechanical properties of DNA components

Physicists from the University of Basel have developed a new method to examine the elasticity and binding properties of DNA molecules on a surface at extremely low temperatures. With a combination of cryo-force spectroscopy and computer simulations, they were able to show that DNA molecules behave like a chain of small coil springs. The researchers reported their findings in Nature Communications.

DNA is not only a popular research topic because it contains the blueprint for life – it can also be used to produce tiny components for technical applications.

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Global Legal Hackathon at HAW Hamburg

11.02.2019 | Event News

The world of quantum chemistry meets in Heidelberg

30.01.2019 | Event News

Our digital society in 2040

16.01.2019 | Event News

 
Latest News

Gravitational waves will settle cosmic conundrum

15.02.2019 | Physics and Astronomy

Spintronics by 'straintronics'

15.02.2019 | Physics and Astronomy

Platinum nanoparticles for selective treatment of liver cancer cells

15.02.2019 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>