Led by John B. Kostis, MD, the John G. Detwiler professor of cardiology, professor of medicine and chair, department of medicine, UMDNJ-Robert Wood Johnson Medical School, this post-hoc analysis of the five-year 10,001 patient TNT study that was funded by Pfizer, Inc., was published in the May 2008 issue of the Journal of Clinical Hypertension.
“People who have both high cholesterol and high blood pressure are at greater risk for cardiovascular disease than those with either condition alone.Yet, a minority of patients with both conditions is treated to currently recommended targets. In one study less than a third of such patients were treated and only one in ten were treated to target,” said Dr. Kostis. “The analysis reported today reminds us that intensive management of both cholesterol and blood pressure, can significantly reduce the risk of heart attacks and strokes.”
Among the 10,001 patients of TNT, 9,739 who had both LDL cholesterol and systolic blood pressure measured at three months after randomization, were included in this analysis. All patients received cholesterol-lowering therapy with atorvastatin calcium (Lipitor®) 80 mg or 10 mg. More than 95 percent of patients in this analysis also were receiving antihypertensive therapy.As reported in the published analysis, patients were divided into groups based on LDL levels (73 mg/dL and lower; 74 to 94 mg/dL; or 95 mg/dL and higher) and systolic blood pressure (140 mmHg and higher, or lower than 140 mmHg) at three months. During a median follow-up of 4.9 years, patients with the lowest LDL and the lowest BP had the lowest risk of major cardiovascular events. For each of the three LDL groups, the rate of cardiovascular events was lower in patients whose systolic blood pressure (SBP) was below 140 mmHg. The benefit of SBP
“Overall, this study provides new evidence of the importance of controlling both dyslipidemia and hypertension” said Dr. Kostis. “However, controlling other risk factors, especially smoking, is still essential to reducing the risk of heart attack and stroke.”
To interview Dr. Kostis, contact Jennifer Forbes at firstname.lastname@example.org or 732-235-6356.
As one of the eight schools of the University of Medicine and Dentistry of New Jersey with 2,500 full-time and volunteer faculty, Robert Wood Johnson Medical School encompasses 22 basic science and clinical departments, hosts centers and institutes including The Cancer Institute of New Jersey, the Child Health Institute of New Jersey, the Center for Advanced Biotechnology and Medicine, the Environmental and Occupational Health Sciences Institute, and the Stem Cell Institute of New Jersey. The medical school maintains educational programs at the undergraduate, graduate and postgraduate levels for more than 1,500 students on its campuses in New Brunswick, Piscataway, and Camden, and provides continuing education courses for health care professionals and community education programs.
Jennifer Forbes | newswise
Graphene gives a tremendous boost to future terahertz cameras
16.04.2019 | ICFO-The Institute of Photonic Sciences
Mount Kilimanjaro: Ecosystems in Global Change
28.03.2019 | Julius-Maximilians-Universität Würzburg
Flexible, organic and printed electronics conquer everyday life. The forecasts for growth promise increasing markets and opportunities for the industry. In Europe, top institutions and companies are engaged in research and further development of these technologies for tomorrow's markets and applications. However, access by SMEs is difficult. The European project SmartEEs - Smart Emerging Electronics Servicing works on the establishment of a European innovation network, which supports both the access to competences as well as the support of the enterprises with the assumption of innovations and the progress up to the commercialization.
It surrounds us and almost unconsciously accompanies us through everyday life - printed electronics. It starts with smart labels or RFID tags in clothing, we...
The human eye is particularly sensitive to green, but less sensitive to blue and red. Chemists led by Hubert Huppertz at the University of Innsbruck have now developed a new red phosphor whose light is well perceived by the eye. This increases the light yield of white LEDs by around one sixth, which can significantly improve the energy efficiency of lighting systems.
Light emitting diodes or LEDs are only able to produce light of a certain colour. However, white light can be created using different colour mixing processes.
Researchers led by Francesca Ferlaino from the University of Innsbruck and the Austrian Academy of Sciences report in Physical Review X on the observation of supersolid behavior in dipolar quantum gases of erbium and dysprosium. In the dysprosium gas these properties are unprecedentedly long-lived. This sets the stage for future investigations into the nature of this exotic phase of matter.
Supersolidity is a paradoxical state where the matter is both crystallized and superfluid. Predicted 50 years ago, such a counter-intuitive phase, featuring...
A stellar flare 10 times more powerful than anything seen on our sun has burst from an ultracool star almost the same size as Jupiter
A localization phenomenon boosts the accuracy of solving quantum many-body problems with quantum computers which are otherwise challenging for conventional computers. This brings such digital quantum simulation within reach on quantum devices available today.
Quantum computers promise to solve certain computational problems exponentially faster than any classical machine. “A particularly promising application is the...
17.04.2019 | Event News
15.04.2019 | Event News
09.04.2019 | Event News
25.04.2019 | Materials Sciences
25.04.2019 | Earth Sciences
25.04.2019 | Life Sciences