A new study of age-related macular degeneration (AMD), a disease that affects more than nine million Americans, will pave the way for the biopharmaceutical industry to develop better treatments and cures, according to the Foundation Fighting Blindness, which partially funded the research.
“This is the first time that scientists have been able to create an AMD animal model that closely represents the disease in people,” said Stephen Rose, Ph.D., Chief Research Officer, Foundation Fighting Blindness. “Though there are some treatments for the wet form of AMD, we still don’t have a cure for the condition, and millions of people are still at risk of losing their vision to both the dry and wet forms. This new model will greatly enhance the development of better treatments and potentially a cure.”
Researchers at the Cleveland Clinic Lerner College of Medicine used oxidative chemicals to sensitize the immune systems in mice and create AMD . The study is titled “Oxidative damage-induced inflammation initiates age-related macular degeneration,” and was published in the online edition of the scientific journal Nature Medicine on January 27.
Once developed, therapies for the dry form, or early stage of AMD, could be implemented before vision is lost, which would be a dramatic breakthrough in the treatment of the disease, Rose said.
David Harrison | EurekAlert!
Study relating to materials testing Detecting damages in non-magnetic steel through magnetism
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Innovative genetic tests for children with developmental disorders and epilepsy
11.07.2018 | Christian-Albrechts-Universität zu Kiel
There are currently great hopes for solid-state batteries. They contain no liquid parts that could leak or catch fire. For this reason, they do not require cooling and are considered to be much safer, more reliable, and longer lasting than traditional lithium-ion batteries. Jülich scientists have now introduced a new concept that allows currents up to ten times greater during charging and discharging than previously described in the literature. The improvement was achieved by a “clever” choice of materials with a focus on consistently good compatibility. All components were made from phosphate compounds, which are well matched both chemically and mechanically.
The low current is considered one of the biggest hurdles in the development of solid-state batteries. It is the reason why the batteries take a relatively long...
New design tool automatically creates nanostructure 3D-print templates for user-given colors
Scientists present work at prestigious SIGGRAPH conference
Most of the objects we see are colored by pigments, but using pigments has disadvantages: such colors can fade, industrial pigments are often toxic, and...
Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...
Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.
When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...
Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.
Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....
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20.08.2018 | Information Technology