Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Promising Alzheimer´s drug trialled in a large EU study

09.12.2013
An extensive European study is currently investigating whether a drug used to treat high blood pressure may also help patients with Alzheimer's disease.

The EU is investing almost 6 million euros on the project, in which Sahlgrenska Academy and Sahlgrenska University Hospital are responsible for Sweden's contribution.

The drug being trialled in the study, nilvadipine, is a well-proven treatment for high blood pressure. Research has shown that nilvadipine counters the formation of amyloid plaques in animal brains.

The drug is now to be trialled with 500 Alzheimer's patients in nine European countries.

... more about:
»Gothenburg »nerve cell

"Should this clinical trial be successful, nilvadipine would become the first Alzheimer's drug that not only reduces the symptoms of the disease but also acts on its causes. This could dramatically reduce Europe's costs for caring for patients with this neurodegenerative disease," says Anne Börjesson-Hanson, a researcher at Sahlgrenska Academy, University of Gothenburg, who is leading the Swedish participation in the study.

The patients in the study will be treated with nilvadipine or a placebo (inactive substance) for eighteen months. Patients who are already being treated with drugs to relieve the symptoms of Alzheimer's will continue to take them as before. Follow-up and check-ups will be carried out at the memory clinic at Sahlgrenska University Hospital.

"We will carry out repeated tests on the patients to see whether there are changes in memory and cognition during the trial period," says Anne Börjesson-Hanson.

This major European research collaboration is called NILVAD, and is being coordinated from Trinity College in Dublin, Ireland. Research teams in the UK, France, Netherlands, Greece, Hungary, Italy and Germany are taking part alongside Ireland and Sweden.

For further information about the project, see:
www.nilvad.eu
ABOUT ALZHEIMER'S DISEASE
Alzheimer's is one of the major widespread diseases. Over 100 000 people are affected in Sweden alone. Europe's ageing population means twice as many people are expected to be affected by 2050. The disease is caused by pathological changes in nerve cells in the brain, affecting memory in particular. The disease often leads to premature death. Alzheimer's causes not only great distress to patients and relatives, but also enormous costs to society.
Contact:
Anne Börjesson-Hanson, lead researcher at Sahlgrenska Academy at the University of Gothenburg, Sweden
+46 31 343 86 69
+46 76 77 66 562
anne.borjesson@neuro.gu.se

Torsten Arpi | idw
Further information:
http://www.gu.se
http://www.sahlgrenska.gu.se/english/news_and_events/news/News_Detail/promising-alzheimer-s-drug-trialled-in-a-large-eu-study.cid119012

Further reports about: Gothenburg nerve cell

More articles from Studies and Analyses:

nachricht Some brain tumors may respond to immunotherapy, new study suggests
11.12.2018 | Columbia University Irving Medical Center

nachricht Climate change and air pollution damaging health and causing millions of premature deaths
30.11.2018 | International Institute for Applied Systems Analysis (IIASA)

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Data storage using individual molecules

Researchers from the University of Basel have reported a new method that allows the physical state of just a few atoms or molecules within a network to be controlled. It is based on the spontaneous self-organization of molecules into extensive networks with pores about one nanometer in size. In the journal ‘small’, the physicists reported on their investigations, which could be of particular importance for the development of new storage devices.

Around the world, researchers are attempting to shrink data storage devices to achieve as large a storage capacity in as small a space as possible. In almost...

Im Focus: Data use draining your battery? Tiny device to speed up memory while also saving power

The more objects we make "smart," from watches to entire buildings, the greater the need for these devices to store and retrieve massive amounts of data quickly without consuming too much power.

Millions of new memory cells could be part of a computer chip and provide that speed and energy savings, thanks to the discovery of a previously unobserved...

Im Focus: An energy-efficient way to stay warm: Sew high-tech heating patches to your clothes

Personal patches could reduce energy waste in buildings, Rutgers-led study says

What if, instead of turning up the thermostat, you could warm up with high-tech, flexible patches sewn into your clothes - while significantly reducing your...

Im Focus: Lethal combination: Drug cocktail turns off the juice to cancer cells

A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth – this was discovered by researchers from the University of Basel’s Biozentrum two years ago. In a follow-up study, recently published in “Cell Reports”, the scientists report that this drug cocktail induces cancer cell death by switching off their energy supply.

The widely used anti-diabetes drug metformin not only reduces blood sugar but also has an anti-cancer effect. However, the metformin dose commonly used in the...

Im Focus: New Foldable Drone Flies through Narrow Holes in Rescue Missions

A research team from the University of Zurich has developed a new drone that can retract its propeller arms in flight and make itself small to fit through narrow gaps and holes. This is particularly useful when searching for victims of natural disasters.

Inspecting a damaged building after an earthquake or during a fire is exactly the kind of job that human rescuers would like drones to do for them. A flying...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

ICTM Conference 2019: Digitization emerges as an engineering trend for turbomachinery construction

12.12.2018 | Event News

New Plastics Economy Investor Forum - Meeting Point for Innovations

10.12.2018 | Event News

EGU 2019 meeting: Media registration now open

06.12.2018 | Event News

 
Latest News

Formed to Meet Customers’ Needs – New Laser Beams for Glass Processing

17.12.2018 | Physics and Astronomy

Preserving soil quality in the long term

17.12.2018 | Architecture and Construction

New RNA sequencing strategy provides insight into microbiomes

17.12.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>