A team of researchers performed MRIs and analyzed the data on the 27 astronauts, each of whom were exposed to microgravity, or zero gravity, for an average of 108 days while on space shuttle missions and/or the International Space Station (ISS), a habitable research facility that has been orbiting the earth since 1998. Eight of the 27 astronauts underwent a second MRI exam after a second space mission that lasted an average of 39 days.
"The MRI findings revealed various combinations of abnormalities following both short- and long-term cumulative exposure to microgravity also seen with idiopathic intracranial hypertension," said Larry A. Kramer, M.D., professor of diagnostic and interventional imaging at The University of Texas Medical School at Houston. "These changes that occur during exposure to microgravity may help scientists to better understand the mechanisms responsible for intracranial hypertension in non-space traveling patients."
Among astronauts with more than 30 days of cumulative lifetime exposure to microgravity, findings included expansion of the cerebral spinal fluid space surrounding the optic nerve in nine of the 27 (33 percent) astronauts, flattening of the rear of the eyeball in six (22 percent), bulging of the optic nerve in four (15 percent) and changes in the pituitary gland and its connection to the brain in three (11 percent) of the astronauts. The pituitary gland secretes and stores hormones that regulate a variety of important body functions.
The same types of abnormalities are observed in cases of intracranial hypertension where no cause can be found for increased pressure around the brain. The pressure causes swelling of the juncture between the optic nerve and the eyeball which can result in visual impairment.
Bone mineral loss and muscle atrophy are some of the known effects of zero gravity on astronauts. With the onset of longer excursions in space afforded by the ISS, visual changes have also been observed and are now being studied.
"Microgravity-induced intracranial hypertension represents a hypothetical risk factor and a potential limitation to long-duration space travel," Dr. Kramer said.
William J. Tarver, M.D., M.P.H., chief of flight medicine clinic at NASA/Johnson Space Center, said the agency has noted changes in vision in some ISS astronauts, the origin of which is not yet fully understood. No astronauts have been considered ineligible for space flight duties as a result of the findings, which he said are suspicious but not conclusive of intracranial hypertension.
"NASA has placed this problem high on its list of human risks, has initiated a comprehensive program to study its mechanisms and implications, and will continue to closely monitor the situation," Dr. Tarver said.
"Orbital and Intracranial Effects of Microgravity: Findings at 3-T MR Imaging." Collaborating with Dr. Kramer were Ashot Sargsyan, M.D., Khader M. Hasan, Ph.D., James D. Polk, D.O., and Douglas R. Hamilton, M.D., Ph.D.
Radiology is edited by Herbert Y. Kressel, M.D., Harvard Medical School, Boston, Mass., and owned and published by the Radiological Society of North America, Inc. (http://radiology.rsna.org/)
RSNA is an association of more than 48,000 radiologists, radiation oncologists, medical physicists and related scientists committed to excellence in patient care through education and research. The Society is based in Oak Brook, Ill. (RSNA.org)
For patient-friendly information on MRI, visit RadiologyInfo.org.
Linda Brooks | EurekAlert!
Innovative genetic tests for children with developmental disorders and epilepsy
11.07.2018 | Christian-Albrechts-Universität zu Kiel
Oxygen loss in the coastal Baltic Sea is “unprecedentedly severe”
05.07.2018 | European Geosciences Union
For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.
To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...
For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.
Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...
Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.
A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...
Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.
"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....
Ultra-short, high-intensity X-ray flashes open the door to the foundations of chemical reactions. Free-electron lasers generate these kinds of pulses, but there is a catch: the pulses vary in duration and energy. An international research team has now presented a solution: Using a ring of 16 detectors and a circularly polarized laser beam, they can determine both factors with attosecond accuracy.
Free-electron lasers (FELs) generate extremely short and intense X-ray flashes. Researchers can use these flashes to resolve structures with diameters on the...
13.07.2018 | Event News
12.07.2018 | Event News
03.07.2018 | Event News
17.07.2018 | Information Technology
17.07.2018 | Materials Sciences
17.07.2018 | Power and Electrical Engineering